Latest posts by Tropical Med and Intl Health (see all)
- The geographic and demographic scope of shared sanitation: an analysis of national survey data… - Aug. 26, 2014
- Non-endemic cases of lymphatic filariasis - Aug. 22, 2014
- Malaria in school-age children in Africa: an increasingly important challenge - Aug. 22, 2014
- Decline in overall, smear-negative and HIV-positive TB incidence while smear-positive incidence… - Aug. 22, 2014
Objectives To determine whether the detection of human IgG bound to Schistosoma haematobium eggs from filtered urine could be used as a rapid diagnostic test (RDT-Sh). Methods We filtered 160 urine samples from children in the Kwale District of Kenya to isolate S. haematobium eggs and used anti-human IgG antibody conjugated to horseradish peroxidase to bind to the human IgG attached to the eggs. We then added 3,35,5-tetramethylbenzidine base (TMB), which turns blue in the presence of horseradish peroxidase to detect the S. haematobium eggs. The RDT-Sh was compared in a blinded manner to urine microscopy.
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