Obesity and Multiple Sclerosis: A Mendelian Randomization Study

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PLoS Medicine

PLoS Medicine

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by Lauren E. Mokry, Stephanie Ross, Nicholas J. Timpson, Stephen Sawcer, George Davey Smith, J. Brent Richards Background Observational studies have reported an association between obesity, as measured by elevated body mass index (BMI), in early adulthood and risk of multiple sclerosis (MS). However, bias potentially introduced by confounding and reverse causation may have influenced these findings.

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Obesity and Multiple Sclerosis: A Mendelian Randomization Study