Serum levels of interleukin-6 are linked to the severity of the disease caused by Andes Virus

The following two tabs change content below.
PLoSNTDs

PLoSNTDs

PLOS Neglected Tropical Diseases is the first open-access journal devoted to the world's most neglected tropical diseases (NTDs), such as elephantiasis, river blindness, leprosy, hookworm, schistosomiasis, and African sleeping sickness. Links to PLoSNTD content is shared via GHHub using the Creative Commons. http://www.plosntds.org/

by Jenniffer Angulo, Constanza Martínez-Valdebenito, Claudia Marco, Héctor Galeno, Eliecer Villagra, Lilian Vera, Natalia Lagos, Natalia Becerra, Judith Mora, Andrea Bermúdez, Janepsy Díaz, Marcela Ferrés, Marcelo López-Lastra Andes virus (ANDV) is the etiological agent of hantavirus cardiopulmonary syndrome in Chile. In this study, we evaluated the profile of the pro-inflammatory cytokines IL-1β, IL-12p70, IL-21, TNF-α, IFN-γ, IL-10 and IL-6 in serum samples of ANDV-infected patients at the time of hospitalization. The mean levels of circulating cytokines were determined by a Bead-Based Multiplex assay coupled with Luminex detection technology, in order to compare 43 serum samples of healthy controls and 43 samples of ANDV-infected patients that had been categorized according to the severity of disease.

Link to article: 

Serum levels of interleukin-6 are linked to the severity of the disease caused by Andes Virus