Discovery by organism based high-throughput screening of new multi-stage compounds affecting…

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PLoSNTDs

PLoSNTDs

PLOS Neglected Tropical Diseases is the first open-access journal devoted to the world's most neglected tropical diseases (NTDs), such as elephantiasis, river blindness, leprosy, hookworm, schistosomiasis, and African sleeping sickness. Links to PLoSNTD content is shared via GHHub using the Creative Commons. http://www.plosntds.org/

by Alessandra Guidi, Cristiana Lalli, Roberto Gimmelli, Emanuela Nizi, Matteo Andreini, Nadia Gennari, Fulvio Saccoccia, Steven Harper, Alberto Bresciani, Giovina Ruberti Schistosomiasis, one of the most prevalent neglected parasitic diseases affecting humans and animals, is caused by the Platyhelminthes of the genus Schistosoma. Schistosomes are the only trematodes to have evolved sexual dimorphism and the constant pairing with a male is essential for the sexual maturation of the female.

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Discovery by organism based high-throughput screening of new multi-stage compounds affecting…