Author Archives: DeafeatDD

The protective power of vaccines against diarrhea

The protective power of vaccines against diarrhea hrandall Mon, 10/09/2017 – 12:08 Oct 09, 2017 Hope Randall Digital Communications Officer for DefeatDD Nicole Maier, clinical trial coordinator for PATH’s enteric vaccine portfolio, said she got choked up while watching our latest video for the first time. Why? I sat down with her to hear more about her personal take on the video.     Talk to me about why you got emotional watching this video.   You know, it just makes everything about organizing clinical trials, from the stressful to the monotonous, worthwhile in the end.

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No time like the present: tackling enteric diseases through integration

No time like the present: tackling enteric diseases through integration hrandall Wed, 10/04/2017 – 13:44 Oct 04, 2017 Zoey Diaz Program Officer, Bill & Melinda Gates Foundation As many of you know, here at the Bill & Melinda Gates Foundation, we are passionate about child health.  We have been encouraged by progress that has been achieved in recent decades: since 1990, the percentage of children who die before age five has been cut in half, primarily through access to better vaccines and treatment in low and middle income countries. However, 50% is not a passing grade. Being an organization of overachievers, we still see much work to do and recognize the great potential to reach more children with proven solutions, as well as new innovations in both tools and delivery systems.

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Rotavirus vaccine – along with our team – demonstrates efficacy in Indian clinical study

Rotavirus vaccine – along with our team – demonstrates efficacy in Indian clinical study hrandall Tue, 09/26/2017 – 11:13 Sep 26, 2017 Tushar Tewari Senior Medical Officer, CVIA Clinical, and PATH’s Team Leader for the BRV-PV Phase 3 efficacy study As results from a Phase 3 efficacy study in India of the Serum Institute of India Pvt. Ltd. (SIIPL)’s rotavirus vaccine BRV-PV (now known as ROTASIIL) are published in the journal Vaccine, I find myself reflecting on the great partnership that conducted the trial. The Serum Institute and PATH worked with six strong community-based clinical sites, all supported by the Clinical Research Organization, DiagnoSearch. 

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After the floods: Diarrheal disease threats lurk behind natural disasters

After the floods: Diarrheal disease threats lurk behind natural disasters hrandall Fri, 09/22/2017 – 13:49 Sep 22, 2017 defeatDD Hurricanes in the United States and the Caribbean. Floods in South Asia and Yemen. Mudslides in Sierra Leone. The natural disasters of the past month have held many captive: literal captives of flooded houses, cars, roads, and airports. Others have been simply captivated by news of the devastation

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Children: the most persistent and passionate advocates

Children: the most persistent and passionate advocates hrandall Tue, 09/12/2017 – 13:32 Sep 12, 2017 Hope Randall Digital Communications Officer for DefeatDD I have yet to meet a child who did not want to be a grown up.   My four-year-old niece, Lily, loves sharing her expertise with her baby sister, Rosalie, on how to navigate the ways of the world. Fortunately for her mom, Lily is fastidious about cleanliness: “I don’t like germs. We don’t need to give germs to each other.” She thinks it’s fun to help Rosalie wash her hands, loves to help her mommy do the dishes, and is loud and proud about her recent potty training success.   As much as she wants to be a grown up, though, she is still only four years old

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An impossible choice: The dangerous disruption of diarrhea treatment costs

An impossible choice: The dangerous disruption of diarrhea treatment costs hrandall Tue, 09/05/2017 – 10:43 Sep 05, 2017 defeatDD Many families are forced to make the impossible choice between treatment and family finances when their children fall ill with diarrheal disease.   Diarrheal disease isn’t just a medical problem—it’s an economic one, too. We’ve heard from families around the world how the costs of diarrhea treatment can significantly interrupt parents’ livelihoods as well as education, food, and shelter for the rest of the family. A study published in the British Medical Journal provides powerful evidence and deeper insights into the economics of diarrheal disease for families in Malawi. To help break it down, we’re sharing a few of the study’s most fascinating findings

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Nutrition and WASH: a recipe for success

Nutrition and WASH: a recipe for success hrandall Wed, 08/30/2017 – 13:53 Aug 30, 2017 Mwandwe Chileshe Global Program Associate at 1,000 Days and a Global Health Corps fellow Originally posted on the 1000 Days website.   In the leadup to World Water Week, WaterAid, SHARE (Sanitation and Hygiene Applied Research for Equity) and Action Against Hunger launched a new report, “The recipe for success,” in which they discuss  a key ingredient for fighting global malnutrition – WASH (water, sanitation and hygiene). The report highlights that 50% of undernutrition in children under five is associated with repeated diarrhea and infections resulting from poor WASH conditions. Additionally, poor sanitation is listed as the second leading cause of stunting worldwide.

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Surprising sanitation lessons in Delhi

Surprising sanitation lessons in Delhi hrandall Thu, 08/24/2017 – 12:33 Aug 24, 2017 Hope Randall Digital Communications Officer for DefeatDD I knew enough to know that Delhi would be unlike any other place I’d ever visited. I knew to expect heart-stopping auto rides, colorful chaos, seemingly impossible juxtapositions of gleaming office buildings and tattered tents, and delicious chai wherever I went. Since Delhi is a dynamic city that cannot be contained physically or conceptually, I should have also expected the unexpected even when it came to sanitation, a topic I know (or thought I knew) well. Tiny open-air vehicles called autos share the road with bikes, motorcycles, and full-sized cars and are not for the faint of heart.  I’d read enough before my trip to know that India’s sanitation situation is a special case in many ways

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Breastfeeding and child survival

Breastfeeding and child survival hrandall Thu, 08/03/2017 – 17:05 Aug 03, 2017 Ruchika Sachdeva Nutrition Team Leader, PATH Ruchika with her daughters, Shyla and Sadhya.   Breastfeeding provides optimal nutrition and is a pillar of child survival. Despite that, in India, only 42 percent of babies are breastfed in the first hour of birth and only half are exclusively breastfed for the first six months. When I see my daughters, Shyla (10) and Sadhya (5), healthy and smart, I know that breastfeeding played a role in laying a solid foundation for their future.

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Child health programs that “color outside the lines”

Child health programs that “color outside the lines” hrandall Thu, 07/27/2017 – 12:14 Jul 27, 2017 Hope Randall Digital Communications Officer for DefeatDD Zari sandwich! PATH team members Cassie Kobrin on the left, Elana Banin on the right.   Nothing was going to keep this DefeatDD team member away from the Hill event, “Ensuring All Children Thrive: A Global Challenge,” which delivered on its promise of muppets, Legos, and ice cream! Co-sponsored by PATH and several partners and true to the ethos of the DefeatDD spirit, the fun-filled atmosphere embodied an important message about child health.

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DefeatDD India videos: Behind-the-scenes commentary

DefeatDD India videos: Behind-the-scenes commentary hrandall Thu, 07/06/2017 – 11:41 Jul 09, 2017 defeatDD Earlier this year, the DefeatDD team journeyed to India to gather stories about the burden of diarrheal disease and the continued need for integrated approaches to prevent the vicious cycle of malnutrition, poverty, and poor health.   While the burden of diarrheal disease in India is among the highest in the world, the national momentum for child health and the programs that are already saving lives filled us with optimism and are a beautiful demonstration of what is possible with the right investments. We hope this video series conveys the inspiration we brought back with us.     Video 1: “Health is our right”: India’s momentum against diarrhea     Hope: We hit the jackpot with partner interviews, but I was personally awestruck by Neerja Chowdhury, a political commentator and journalist who has been a passionate advocate against child malnutrition for 30+ years. I was grateful for the opportunity to feature so many Indian voices in these videos, especially Indian women

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Telling the world’s most vulnerable children, “We’re in your corner.”

Telling the world’s most vulnerable children, “We’re in your corner.” hrandall Thu, 06/29/2017 – 12:16 Jun 29, 2017 Six years ago, I traveled through rural Western Kenya to gather stories about Alfred Ochola’s one-man mission to restore oral rehydration therapy (ORT) corners in local hospitals. Though I was there to listen and observe, Alfred handed me a hot plate before we entered each clinic and gave me the honor of presenting it to grateful staff (the hot plates facilitated the nurses’ ability to make a healthy meal for recovering ORT therapy patients before discharging them). He reasoned that since the hot plates came from USAID, it would be meaningful if I, a US citizen whose tax dollars had contributed to these supplies, would deliver them. As an individual, I felt humbled.

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How cost-effectiveness analysis helped strengthen Bangladesh’s resolve to combat rotavirus

How cost-effectiveness analysis helped strengthen Bangladesh’s resolve to combat rotavirus hrandall Wed, 06/14/2017 – 15:56 Jun 14, 2017 Umesh Parashar Head of the Viral Gastroenteritis team in the Division of Viral Diseases, US Centers for Disease Control and Prevention (CDC) In the lead-up to Bangladesh’s introduction of rotavirus vaccines, a recently published cost-effectiveness analysis helps bolster the evidence base for decision-makers.   Bangladesh has long played a leading role in building the evidence base for interventions to combat diarrheal disease. This includes early groundbreaking research on oral rehydration solution as well as a pivotal RotaTeq® rotavirus vaccine effectiveness trial that contributed to the 2009 World Health Organization (WHO) recommendation for global rotavirus vaccination. Researchers in Bangladesh also recently completed an effectiveness trial of Rotarix® in Bangladesh to round out the evidence. So it is no surprise that Bangladesh is once again taking a leading role in its upcoming introduction of rotavirus vaccines

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How we measure the true impact of diarrheal diseases

How we measure the true impact of diarrheal diseases hrandall Wed, 06/07/2017 – 10:56 Jun 07, 2017 Ibrahim Khalil Institute for Health Metrics and Evaluation, University of Washington Puja Rao Institute for Health Metrics and Evaluation, University of Washington   The problem: One-time illness or lifelong impairment?   When a child experiences a single episode of diarrhea, they typically feel uncomfortable for a short period of time, but with appropriate care, they recover and continue to live a life free from disability. But when access to safe water and sanitation is limited—and children are constantly exposed to an assortment of bacteria and viruses—what happens when a child experiences frequent bouts of diarrhea without proper remedy? To answer this question, we need to better understand the cyclical relationship of diarrheal diseases and enteric infections during the crucial period of early childhood development and related poor health outcomes that can result over a lifetime.

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