Author Archives: JAIDS

How Relevant is the Interaction Between Dolutegravir and Metformin in Real Life?

No abstract available

Posted in Journal Watch | Comments closed

Characteristics and Outcome of a Cohort of HIV-1 Non-B Subtype–Infected Patients After a…

No abstract available

Posted in Journal Watch | Comments closed

Trends in Responses to DHS Questions Should Not Be Interpreted as Reflecting an Increase in…

No abstract available

Posted in Journal Watch | Comments closed

Brief Report: Changes in Levels of Inflammation After Antiretroviral Treatment During Early…

Background: We evaluated the changes in the levels of soluble biomarkers of inflammation and coagulation and T-cell activation among participants of AIDS Clinical Trials Group Study A5217 who were started on antiretroviral therapy (ART) within the first 6 months of HIV infection.

Posted in Journal Watch | Comments closed

Effect of Pregnancy on Interferon Gamma Release Assay and Tuberculin Skin Test Detection of…

Background: Peripartum immunologic changes may affect latent tuberculosis infection (LTBI) diagnostic performance among HIV-infected women.

Posted in Journal Watch | Comments closed

Hemeoxygenase-1 as a Novel Driver in Ritonavir-Induced Insulin Resistance in HIV-1–Infected…

Background: Hemeoxygenase-1 (HO-1) has recently been identified as a major driver of metaflammation and obesity-related insulin resistance (IR).

Posted in Journal Watch | Comments closed

Neutralizing and Targeting Properties of a New Set of α4β7-Specific Antibodies Are Influenced…

Abstract: The homing of lymphocytes to the mucosa is mainly controlled by α4β7 integrin, and it is amplified during gut chronic inflammation, as occurs with HIV and/or inflammatory bowel diseases.

Posted in Journal Watch | Comments closed

Hormonal contraception does not reduce antiretroviral effectiveness

Background: To explore the association between concomitant hormonal contraceptive and antiretroviral therapy (ART) use and (1) plasma viral suppression and (2) genital HIV shedding among HIV-positive women initiating ART.

Posted in Gender, HIV/AIDS, Infectious Disease, Journal Watch, Social | Tagged , | Comments closed

The Relationship Between Injection Drug Use and Immune Activation

Abstract: High levels of immune activation are reported for people who inject drugs.

Posted in HIV/AIDS, Infectious Disease, Journal Watch, Noncommunicable Disease, Tobacco, alcohol, & drugs | Tagged , | Comments closed

Real-World Efficacy of Daclatasvir and Sofosbuvir, With and Without Ribavirin, in HIV/HCV…

Background: Efficacious, well-tolerated, direct antiviral agents have drastically changed the prognosis of hepatitis C virus (HCV) disease, but real-world data for oral treatments are limited in key populations such as HIV/HCV coinfection with advanced liver disease.

Posted in Journal Watch | Comments closed

Brief Report: Longitudinal Opioid Use Among HIV-Infected Patients, 2000 to 2014

Abstract: Longitudinal opioid prescription use is unknown among HIV-infected patients.

Posted in Journal Watch | Comments closed

Gastrointestinal Symptom Distress is Associated With Worse Mental and Physical Health-Related…

Background: The prevalence of self-reported gastrointestinal (GI) symptoms and distress is high, but few studies have quantified their impact on health-related quality of life (HRQoL).

Posted in Journal Watch | Comments closed

Antiviral Activity, Safety, and Pharmacokinetics of Bictegravir as 10-Day Monotherapy in…

Objective: To evaluate antiviral activity, safety, and pharmacokinetics of short-term monotherapy with bictegravir (BIC), a novel, potent HIV integrase strand transfer inhibitor (INSTI).

Posted in Journal Watch | Comments closed

The Second-Generation Maturation Inhibitor GSK3532795 Maintains Potent Activity Toward HIV…

Background: Protease inhibitor (PI)-resistant HIV-1 isolates with primary substitutions in protease (PR) and secondary substitutions in Gag could potentially exhibit cross-resistance to maturation inhibitors.

Posted in Journal Watch | Comments closed