Author Archives: JAIDS

HIV and Aging: Demographic Change in the Asia-Pacific Region

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Direct Targeting of Macrophages With Methylglyoxal-Bis-Guanylhydrazone Decreases SIV-Associated…

Background: Despite effective combination antiretroviral therapy, HIV-infected individuals develop comorbidities, including cardiovascular disease, where activated macrophages play a key role.

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Granulocytic Myeloid–Derived Suppressor Cells Increased in Early Phases of Primary HIV…

Background: It has been demonstrated that myeloid-derived suppressor cells (MDSC) are expanded in HIV-1–infected individuals and correlated with disease progression.

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Brief Report: Pharmacokinetics of Crushed Elvitegravir Combination Tablet Given With or…

Abstract: We investigated whether a fixed-dose combination tablet of elvitegravir, cobicistat, emtricitabine, and tenofovirDF (Stribild) can be crushed and combined with enteral nutrition without influencing pharmacokinetics.

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Regionally Specific Brain Volumetric and Cortical Thickness Changes in HIV-Infected Patients in…

Background: Cognitive impairment still occurs in a substantial subset of HIV-infected patients, despite effective viral suppression with highly active antiretroviral therapy (HAART).

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Loss to Follow-up Trends in HIV-Positive Patients Receiving Antiretroviral Treatment in Asia…

Introduction: Over time, there has been a substantial improvement in antiretroviral treatment (ART) programs, including expansion of services and increased patient engagement.

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Evaluation of a Predictive Staging Model for HIV-Associated Kaposi Sarcoma in Uganda

Background: HIV-associated Kaposi sarcoma (KS) is commonly staged using the AIDS Clinical Trials Group criteria, which classify 3 variables— tumor extent (T), immune status (I), and systemic symptoms (S)—into good risk (0) and poor risk (1).

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Baseline Vitamin D Deficiency Decreases the Effectiveness of Statins in HIV-Infected Adults on…

Objective: Vitamin D deficiency is common in HIV.

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Healthcare Access and PrEP Continuation in San Francisco and Miami After the US PrEP Demo…

Background: Pre-exposure prophylaxis (PrEP) for prevention of HIV infection has demonstrated efficacy in randomized controlled trials and in demonstration projects.

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Implementation of Antiretroviral Therapy for Life in Pregnant/Breastfeeding HIV+ Women (Option…

Background: Lifelong antiretroviral therapy (ART) for pregnant and breastfeeding women (Option B+) was rolled out in Zimbabwe from 2014, with simultaneous raising of the CD4 treatment threshold to 500 cells per cubic millimeter in nonpregnant/breastfeeding adults and children 5 years and over.

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Public Health Benefit of Peer-Referral Strategies for Detecting Undiagnosed HIV Infection Among…

Abstract: Identifying undiagnosed HIV infection is necessary for the elimination of HIV transmission in the United States.

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Nevirapine Pharmacokinetics and Safety in Neonates Receiving Combination Antiretroviral Therapy…

Background: Nevirapine (NVP)-based combination antiretroviral therapy is routinely prescribed to infants deemed at high risk of vertical HIV infection in our centers.

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Brief Report: Association Between Menopause and Unprotected Sex in High-Risk HIV-Positive…

Objective: Many HIV-positive women now live well beyond menopause.

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High Mobility and HIV Prevalence Among Female Market Traders in East Africa in 2014

Background: The contribution of women’s mobility to the HIV/AIDS epidemic in Africa is poorly understood, despite women’s high mobility and evidence that it is associated with higher-risk sexual behavior.

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