Author Archives: JAIDS

Stabilizing Incidence of Hepatitis C Virus Infection Among Men Who Have Sex With Men in…

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Relationship Between Hyperglycemia and the Risk of Tuberculosis in Asian HIV-Positive…

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Scale-up of Adolescent Contraceptive Services: Lessons from a 5-Country Comparative Analysis: …

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Impact of Isoniazid Preventive Therapy for HIV-Infected Adults in Rio de Janeiro, Brazil: An…

Background: The potential epidemiological impact of isoniazid preventive therapy (IPT), delivered at levels that could be feasibly scaled up among people living with HIV (PLHIV) in modern, moderate-burden settings, remains uncertain.

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Study Product Adherence Measurement in the iPrEx Placebo-Controlled Trial: Concordance With…

Objective: To evaluate the concordance between adherence estimated by self-report (in-person interview or computer-assisted self-interview), in-clinic pill counts, and pharmacy dispensation records and drug detection among participants in a placebo-controlled pre-exposure prophylaxis HIV prevention trial (iPrEx).

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An Intervention to Support HIV Preexposure Prophylaxis Adherence in HIV-Serodiscordant Couples…

Background: Daily preexposure prophylaxis (PrEP) is an effective HIV prevention strategy, but adherence is required for maximum benefit.

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Safety of Cotrimoxazole in Pregnancy: A Systematic Review and Meta-Analysis

Introduction: Cotrimoxazole is widely prescribed to treat a range of infections, and for HIV-infected individuals it is administered as prophylaxis to protect against opportunistic infections.

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Reliability and Validity of Depression Assessment Among Persons With HIV in Sub-Saharan Africa:…

Objective: The aim of this study was to systematically review the reliability and validity of instruments used to screen for major depressive disorder or assess depression symptom severity among persons with HIV in sub-Saharan Africa.

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Low Raltegravir Concentration in Cerebrospinal Fluid in Patients With ABCG2 Genetic Variants

Abstract: Adenosine triphosphate–binding cassette transporter G2 (ABCG2) is expressed on the cerebrospinal fluid (CSF) side of choroid plexus epithelial cells, which form the blood–CSF barrier.

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Rational Design and Characterization of the Novel, Broad and Potent Bispecific HIV-1…

Background: Although broadly neutralizing monoclonal antibodies (bNAbs) have always been considered to be a potential therapeutic option for the prophylaxis and treatment of HIV infection, their lack of breadth against all HIV variants has been one of the limiting factors.

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Effects of Different Antigenic Stimuli on Thymic Function and Interleukin-7/CD127 System in…

Background: We tested if an increase in immune activation and a decrease in CD4+ T cells induced by different antigenic stimuli could be associated with changes in the thymic function and the interleukin (IL)-7/CD127 system.

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A 48-Week Study of Fat Molecular Alterations in HIV Naive Patients Starting…

Background: Conflicting reports on the effects of efavirenz (EFV) and lopinavir/ritonavir (LPV/r) on subcutaneous adipose tissue (SAT) have been described.

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Long-Chain Peer Referral to Recruit Black MSM and Black Transgender Women for an HIV Vaccine…

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CD4 T-Lymphocyte Percentages Corresponding to CD4 T-Lymphocyte Count Thresholds in a New…

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