Author Archives: Lancet Global Health

Financing of international collective action for #epidemic and pandemic #preparedness

The global pandemic response has typically followed cycles of panic followed by neglect. We are now, once again, in a phase of neglect, leaving the world highly vulnerable to massive loss of life and economic shocks from natural or human-made epidemics and pandemics. Quantifying the size of the losses caused by large-scale outbreaks is challenging because the epidemiological and economic research in this field is still at an early stage. Research on the 1918 influenza H1N1 pandemic and recent epidemics and pandemics has shown a range of estimated losses (panel).

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[Corrections] Correction to 2017; published online April 30,…

Dokainish H, Teo K, Zhu J, et al, on behalf of the INTER-CHF Investigators. Global mortality variations in patients with heart failure: results from the International Congestive Heart Failure (INTER-CHF) prospective cohort study. Lancet Glob Health 2017; published online April 30, http://dx.doi.org/10.1016/S2214-109X(17)30196-1—In this Article, the date at the top of the address box in the far right column should have been Lancet Glob Health 2017. This change has been made to the online version as of May 9, 2017.

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[Comment] Double-duty actions for ending malnutrition within a decade

Malnutrition has many forms. Undernutrition can see children dangerously thin for their height (wasting), or their growth permanently impeded (stunting). Inadequate intake of key nutrients may weaken immune systems, impair brain development, and worsen the risk of conditions such as anaemia and blindness. Diets rich in calories well beyond the body’s metabolic needs drive the burden of overweight and obesity, while excess dietary fat, sugar, and salt can increase the risks of non-communicable diseases (NCDs).

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Global mortality variations in patients with heart failure

Marked regional differences in mortality in patients with heart failure persisted after multivariable adjustment for cardiac and non-cardiac factors. Therefore, variations in mortality between regions could be the result of health-care infrastructure, quality and access, or environmental and genetic factors. Further studies in large, global cohorts are needed.

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[Corrections] Correction to 2016; 4: e453–63

Bruni L, Diaz M, Barrionuevo-Rosas L, et al. Global estimates of human papillomavirus vaccination coverage by region and income level: a pooled analysis. Lancet Glob Health 2016; 4: e453–63—In this Article, a missing affiliation has been added for Laila Bruni. This correction has been made to the online version as of April 26, 2017.

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[Comment] Mental health—a bridge not so far

The world now faces the next step in HIV management. We are in an era beyond treatment and viral suppression. The widespread roll out of antiretroviral treatment and good HIV testing programmes within pregnancy might substantially change vertical transmission rates globally. Lifelong treatment and innovations, such as those financed by the Global Fund, provide a pathway— indeed a lifeline—for survival. Yet, the scars of an epidemic are deep.

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[Comment] Recognising the role of community-directed treatment and of women in the fight…

This year allows recognition and celebration of two key factors behind recent improvements in the health and wellbeing of marginalised people: the ivermectin donation programme for onchocerciasis and the role of women in the success of this and other strategies to combat neglected tropical diseases (NTDs).

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[Articles] Progress and inequities in maternal mortality in Afghanistan (RAMOS-II): a…

Remarkable maternal and other mortality reductions have occurred in Afghanistan, but the disparity between urban and rural sites is alarming, with all maternal mortality indicators significantly higher in Ragh than in Kabul. Customised service delivery is needed to ensure parity for different geographic and security settings.

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[Articles] Pathways between childhood trauma, intimate partner violence, and harsh parenting:…

The data point to both a co-occurrence and a cycle of abuse, with childhood trauma leading to violence against women and further child maltreatment, which in turn increases the risk of experience or perpetration of violence during adulthood. Efforts to prevent both forms of violence would benefit from a meaningful integrated approach. Interventions should promote positive parenting, address inequality and the normalisation of violence across the life course, and transform men’s power over women and children.

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[Articles] Complementary feeding at 4 versus 6 months of age for preterm infants born at less…

Although there was no evidence of effect for the primary endpoint of WAZ12, the higher rate of hospital admission in the 4 month group suggests a recommendation to initiate complementary feeding at 6 months over 4 months of corrected age in infants less than 34 weeks of gestation.

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[Articles] Effect of co-trimoxazole on mortality in HIV-exposed but uninfected children in…

Prophylactic co-trimoxazole seems to offer no survival benefit among HEU children in non-malarial, low-breastfeeding areas with a low risk of mother-to-child transmission of HIV.

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[Corrections] Correction to Lancet Glob Health 2016; 4: e378–85

Gichuhi S, Macharia E, Kabiru J, et al. Topical fluorouracil after surgery for ocular surface squamous neoplasia in Kenya: a randomised, double-blind, placebo-controlled trial. Lancet Glob Health 2016; 4: e378–85—In this Article, the definition of CIN in table 1 should have read “CIN=conjunctival intra-epithelial neoplasia”. This correction has been made to the online version as of April 7, 2017.

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