Author Archives: PLoS Medicine Blog

Introducing a New Look for the Journal Homepages

Today sees the launch of our re-vamped homepages for PLOS Medicine, PLOS Pathogens and PLOS Neglected Tropical Diseases. They’ve been designed to give easy access to all recently published work, and to better incorporate some of the beautiful images …The post Introducing a New Look for the Journal Homepages appeared first on Speaking of Medicine.

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World Hepatitis Day 2014 – Think Again

A former hepatitis virus researcher reminisces on the progress made and challenges remaining in the fight to eradicate chronic viral hepatitis. July 28, 2014.  “Hepatitis: Think Again.”  That is the motto for this year’s World Hepatitis Day, a program …The post World Hepatitis Day 2014 – Think Again appeared first on Speaking of Medicine.

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Visit PLOS at IUMS 2014 in Montréal

We are pleased to announce that PLOS Pathogens will be exhibiting at the International Union of Microbiological Societies (IUMS), July 27th – August 1st in Montréal. IUMS unites 3 international congresses of bacteriology and applied microbiology, mycology and eukaryotic microbiology, …The post Visit PLOS at IUMS 2014 in Montréal appeared first on Speaking of Medicine.

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Millennium Development Goal 6: Measuring Progress

One of the most dramatic international responses to the Millennium Development Goals launched by then United Nations Secretary Kofi Annan in 2000 has been the global public health community’s response to MDG 6 “To combat AIDS, malaria and other diseases” [1].  …The post Millennium Development Goal 6: Measuring Progress appeared first on Speaking of Medicine.

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Evidently it’s Cholera Season

Just when the oppressive summer heat and humidity in South Asia seem no longer tolerable, especially to this Northern expatriate new to Bangladesh, the rains come, bringing relief in the form of cooler temperatures, fresh air, and sparkling trees and …The post Evidently it’s Cholera Season appeared first on Speaking of Medicine.

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PLOS launches Clinical Immunology Collection

Nathaniel Gore, Editorial Project Manager of PLOS Collections, on the launch of a new Clinical Immunology Collection Image Credit: NIAID/NIH, Wikimedia Commons / PLOS Today PLOS launches a new Collection – the Clinical Immunology Collection. Following on from the successful redevelopment of the Synthetic Biology Collection, and responding to the commonly articulated request from our users that we provide more structured and efficient access to papers of interest in the PLOS corpus, the Clinical Immunology Collection is organized into several sub-disciplines, enabling researchers to easily locate the research they seek. To this end, the Clinical Immunology Collection launches today with sections on Allergies & Anaphylaxis and Tumor Immunology. The Collection has been seeded with previously published PLOS content – from across the suite of PLOS journals – and will be expanded as new research and commentary is published by PLOS. Furthermore, the collection will see the addition of further Clinical Immunology subsections – including Immunodeficiency Syndromes, Autoimmune Conditions, Infectious Disease Immunology, Immunomodulatory Treatments and Transplant Immunology – and, later in the year, the addition of an Immunobiology Collection which will include sections on Cellular and Molecular Immunology, Evolutionary Immunology, Animal Models of the Human Immune System and Immune System Ontogeny. To find out more about the Collection contact collections@plos.org or, if you are at FOCiS 2014 this week, please drop by Booth 115 to receive a complimentary USB drive containing articles published by PLOS authored by FOCiS 2014 presenters, and selected articles from the corpus of clinical immunology research published by PLOS.

Posted in Aid, Infectious Disease, Journal Watch, Publications | Tagged , , | Comments closed

From One to One Million Article Views: Q&A with Author John Ioannidis

PLOS’s Erica Kritsberg interviews John Ioannidis about the success of his article “Why Most Published Research Findings Are False”, which reached one million views in April this year. John Iaonnidis “Why Most Published Research Findings Are False”, the PLOS Medicine article by John Ioannidis, surpassed one million views late April 2014, the first PLOS article – research or other – to reach this milestone. First published Aug. 30, 2005, it has continued to influence thinking and inspire debate in the field and beyond. To commemorate this achievement, Ioannidis, C

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Book Review: The Adventure of the Cure That Wasn’t

Marzieh Ghiasi and Madhukar Pai from McGill University & McGill International TB Centre, Montreal, review “The Remedy” by Thomas Goetz Robert Koch raised the hopes of millions of tuberculosis patients with his remedy (i.e. tuberculin) that turned out to be ineffective. Today, tuberculin is a widely used diagnostic test for latent tuberculosis infection (picture). Image credit: Madhukar Pai No image is more iconic of the Victorian age than that of a detective with a deerstalker cap, pipe, and magnifying glass roaming the dark streets of London in search of criminals and murderers. Hidden in plain sight, the real killers of the nineteenth century were infectious diseases such as tuberculosis, responsible for as many as a quarter of all deaths in that era.

Posted in Competition, Conferences, Environment, Infectious Disease, Journal Watch, Mental Health, Online, Publications, Tuberculosis, Vaccines | Tagged , , , , , , , , , | Comments closed

EH!WOZA: Leaving the Lab and Addressing TB Stigmas and Taboos

Anastasia Koch, a molecular biology PhD student in South Africa talks about engaging the community with biomedical research. Ikamva Youth on a visit to MMRU labs As a molecular biology – molecular mycobacteriology to be precise – PhD student, I never thought I’d be involved in the production of documentaries & online media resources. In the past few months, I’ve uncharacteristically found myself critiquing aesthetics in film and design owing to an involvement in a unique collaboration between biomedical scientists, artists, and a community not-for-profit organisation. Let me begin with some background. I work in the Molecular Mycobacteriology Research Unit (MMRU) of the Institute of Infectious Diseases and Molecular Medicine at the University of Cape Town.

Posted in Environment, Funding, General Global Health, Infectious Disease, Journal Watch, Online, Poverty, Social, Tuberculosis | Tagged , , , , , , , , , , , , , , , | Comments closed

I’m a Scientist with Learning Disabilities and That’s Okay!

Post doc Collin Diedrich discusses his experiences as a learning disabled scientist. Image credit: Collin Diedrich About a month ago, I was playing with my 3yr old niece, drawing pictures with Crayola Crayons. She pulled out a purplish color and asked me what it was. I dutifully read the name, as phonetically as I could, “MAG-A-NEAT-A… what the hell is MAG-A-NEAT-A?” We all laughed, and my brother (the dad) intervened: “It’s MA-GEN-TA.” I told my niece I probably am not the best person to read her these names.

Posted in Environment, Journal Watch, Online, Tuberculosis | Tagged , , , , , , | Comments closed

I’m a Scientist with Learning Disabilities and That’s Okay!

Post doc Collin Diedrich discusses his experiences as a learning disabled scientist. Image credit: Collin Diedrich About a month ago, I was playing with my 3yr old niece, drawing pictures with Crayola Crayons. She pulled out a purplish color and asked me what it was. I dutifully read the name, as phonetically as I could, “MAG-A-NEAT-A… what the hell is MAG-A-NEAT-A?” We all laughed, and my brother (the dad) intervened: “It’s MA-GEN-TA.” I told my niece I probably am not the best person to read her these names.

Posted in Environment, Journal Watch, Online, Tuberculosis | Tagged , , , , , , | Comments closed

Everything You Always Wanted to See about Sex in Leishmania

Geneviève Lanotte (retired), Jean-Antoine Rioux (retired), and Jérémy Bouyer from CIRAD recount that cellular fusion in Leishmania was filmed in the 80s and provide the sex movie to the scientific community. The title of our comment refers to the humorous title of the Review by Rougeron et al. (2010) on the sexuality of Leishmania: Everything You Always Wanted to Know about Sex (but Were Afraid to Ask)” in Leishmania after Two Decades of Laboratory and Field Analyses. In this paper, the authors present recent works challenging the dogmatic hypothesis of “dominant and ancient clonal reproductive mode”. Amazing animations already exist to illustrate the clonal reproduction cycle of Leishmania.

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An Open Letter to the EMA from the AllTrials Steering Committee

AllTrials campaign c/o Sense About Science 14A Clerkenwell Green London EC1R 0DP alltrials@senseaboutscience.org Professor Guido Rasi Director, European Medicines Agency 7 Westferry Circus Canary Wharf London E14 4HB 2nd June 2014 Dear Professor Rasi Re: Draft Publication and access to clinical-trial data policy (EMA/240810/2013) Hundreds of supporters of the AllTrials campaign contributed last year to the Agency’s consultation on its draft policy “Publication and access to clinical-trial data.” We welcomed the EMA’s proposals which would have seen Clinical Study Reports published proactively and openly in line with an Agency policy that the information in those reports should not generally be considered commercially confidential. We are now concerned that the most recent draft of the policy as shared with some stakeholders at meetings this month introduces barriers that will make it all but useless to independent researchers. We understand that there are four areas of particular concern: 1. Clinical Study Reports will only be available for viewing on screen and cannot be saved, downloaded, printed, copied, annotated or shared in any way.

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The Failures and Futures of the Peer Review Process

Elspeth K. Ritchie from Newcastle University’s Biopharmaceutical Bioprocessing Technology Centre reflects on discussions between academic journal editors and writers after attending the Voice of Young Science “Peer Review: Nuts & Bolts” workshop, which was supported by several organisations including PLOS. The words “peer review process” mean different things throughout a scientist’s career. For the established professor, it may be a well worn path. Meanwhile, it strikes terror into those preparing to submit for the first time

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