Author Archives: PLoSNTDs

Wetlands, wild Bovidae species richness and sheep density delineate risk of Rift Valley fever…

by Michael G. Walsh, Allard Willem de Smalen, Siobhan M. Mor Rift Valley fever (RVF) is an emerging, vector-borne viral zoonosis that has significantly impacted public health, livestock health and production, and food security over the last three decades across large regions of the African continent and the Arabian Peninsula.

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Risk of exposure to potential vector mosquitoes for rural workers in Northern Lao PDR

by Julie-Anne A. Tangena, Phoutmany Thammavong, Steve W. Lindsay, Paul T

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A putative ATP/GTP binding protein affects <i>Leishmania mexicana</i> growth in…

by Aygul Ishemgulova, Natalya Kraeva, Jana Hlaváčová, Sara L. Zimmer, Anzhelika Butenko, Lucie Podešvová, Tereza Leštinová, Julius Lukeš, Alexei Kostygov, Jan Votýpka, Petr Volf, Vyacheslav Yurchenko Background Leishmania virulence factors responsible for the complicated epidemiology of the various leishmaniases remain mainly unidentified.

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Type 1-skewed neuroinflammation and vascular damage associated with <i>Orientia…

by Lynn Soong, HeThomas R. Shelite, Yan Xing, Harica Kodakandla, Yuejin Liang, Brandon J.

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Pathological manifestations in lymphatic filariasis correlate with lack of inhibitory…

by Ulrich F. Prodjinotho, Charlotte von Horn, Alex Y.

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Insecticide resistance is mediated by multiple mechanisms in recently introduced <i>Aedes…

by Gonçalo Seixas, Linda Grigoraki, David Weetman, José Luís Vicente, Ana Clara Silva, João Pinto, John Vontas, Carla Alexandra Sousa Background Aedes aegypti is a major mosquito vector of arboviruses, including dengue, chikungunya and Zika. In 2005, Ae. aegypti was identified for the first time in Madeira Island

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Molecular and MALDI-TOF identification of ticks and tick-associated bacteria in Mali

by Adama Zan Diarra, Lionel Almeras, Maureen Laroche, Jean-Michel Berenger, Abdoulaye K. Koné, Zakaria Bocoum, Abdoulaye Dabo, Ogobara Doumbo, Didier Raoult, Philippe Parola Ticks are considered the second vector of human and animal diseases after mosquitoes. Therefore, identification of ticks and associated pathogens is an important step in the management of these vectors

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Epidemiology, clinical features and risk factors for human rabies and animal bites during an…

by Cristolde Salomão, Amílcar Nacima, Lutero Cuamba, Lorna Gujral, Olga Amiel, Cynthia Baltazar, Julie Cliff, Eduardo Samo Gudo Background In Mozambique, the majority of rabies outbreaks are unreported and data on the epidemiological features of human rabies and animal bites are scarce. An outbreak of human rabies in adjacent Maputo and Matola cities in 2014 prompted us to investigate the epidemiology, clinical features and risk factors of human rabies and animal bites in the two cities. Methodology/Principal findings We reviewed cases of human rabies and animal bites from April to July 2014, and carried out a community investigation in July and August in the neighborhoods where cases of human rabies resided.

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Epidemiology of enteroaggregative <i>Escherichia coli</i> infections and associated…

by Elizabeth T. Rogawski, Richard L. Guerrant, Alexandre Havt, Ila F

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Disease severity in patients with visceral leishmaniasis is not altered by co-infection with…

by Fitsumbrhan Tajebe, Mulusew Getahun, Emebet Adem, Asrat Hailu, Mulualem Lemma, Helina Fikre, John Raynes, Aschalew Tamiru, Zemenay Mulugeta, Ermias Diro, Frederic Toulza, Ziv Shkedy, Tadesse Ayele, Manuel Modolell, Markus Munder, Ingrid Müller, Yegnasew Takele, Pascale Kropf Visceral leishmaniasis (VL) is a neglected tropical disease that affects the poorest communities and can cause substantial morbidity and mortality. Visceral leishmaniasis is characterized by the presence of Leishmania parasites in the spleen, liver and bone marrow, hepatosplenomegaly, pancytopenia, prolonged fever, systemic inflammation and low body mass index (BMI). The factors impacting on the severity of VL are poorly characterized

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Effects of liver-stage clearance by Primaquine on gametocyte carriage of <i>Plasmodium…

by Rahel Wampfler, Natalie E. Hofmann, Stephan Karl, Inoni Betuela, Benson Kinboro, Lina Lorry, Mariabeth Silkey, Leanne J. Robinson, Ivo Mueller, Ingrid Felger Background Primaquine (PQ) is the only currently licensed antimalarial that prevents Plasmodium vivax (Pv) relapses.

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Analysis of patient data from laboratories during the Ebola virus disease outbreak in Liberia,…

by Yuki Furuse, Mosoka Fallah, Hitoshi Oshitani, Ling Kituyi, Nuha Mahmoud, Emmanuel Musa, Alex Gasasira, Tolbert Nyenswah, Bernice Dahn, Luke Bawo An outbreak of Ebola virus disease (EVD) in Liberia began in March 2014 and ended in January 2016. Epidemiological information on the EVD cases was collected and managed nationally; however, collection and management of the data were challenging at the time because surveillance and reporting systems malfunctioned during the outbreak.

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Drivers for Rift Valley fever emergence in Mayotte: A Bayesian modelling approach

by Raphaëlle Métras, Guillaume Fournié, Laure Dommergues, Anton Camacho, Lisa Cavalerie, Philippe Mérot, Matt J. Keeling, Catherine Cêtre-Sossah, Eric Cardinale, W.

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Contemporary status of insecticide resistance in the major <i>Aedes</i> vectors of…

by Catherine L. Moyes, John Vontas, Ademir J.

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