Author Archives: PLoSNTDs

Longitudinal survey of two serotine bat (<i>Eptesicus serotinus</i>) maternity…

by Emmanuelle Robardet, Christophe Borel, Marie Moinet, Dorothée Jouan, Marine Wasniewski, Jacques Barrat, Franck Boué, Elodie Montchâtre-Leroy, Alexandre Servat, Olivier Gimenez, Florence Cliquet, Evelyne Picard-Meyer This study describes two longitudinal serological surveys of European Bat Lyssavirus type 1 (EBLV-1) antibodies in serotine bat (Eptesicus serotinus) maternity colonies located in the North-East of France. This species is currently considered as the main EBLV-1 reservoir.

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Mycolactone displays anti-inflammatory effects on the nervous system

by Caroline Isaac, Annie Mauborgne, Alfonso Grimaldi, Kemy Ade, Michel Pohl, Cristina Limatola, Yves Boucher, Caroline Demangel, Laure Guenin-Macé Background Mycolactone is a macrolide produced by the skin pathogen Mycobacterium ulcerans, with cytotoxic, analgesic and immunomodulatory properties. The latter were recently shown to result from mycolactone blocking the Sec61-dependent production of pro-inflammatory mediators by immune cells. Here we investigated whether mycolactone similarly affects the inflammatory responses of the nervous cell subsets involved in pain perception, transmission and maintenance

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The introduction of dengue follows transportation infrastructure changes in the state of Acre,…

by Raquel Martins Lana, Marcelo Ferreira da Costa Gomes, Tiago França Melo de Lima, Nildimar Alves Honório, Cláudia Torres Codeço Human mobility, presence and passive transportation of Aedes aegypti mosquito, and environmental characteristics are a group of factors which contribute to the success of dengue spread and establishment. To understand this process, we assess data from dengue national and municipal basins regarding population and demographics, transportation network, human mobility, and Ae. aegypti monitoring for the Brazilian state of Acre since the first recorded dengue case in the year 2000 to the year 2015

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Detection of relapsing fever <i>Borrelia</i> spp., <i>Bartonella</i>…

by Ismail Lafri, Basma El Hamzaoui, Idir Bitam, Hamza Leulmi, Reda Lalout, Oleg Mediannikov, Mohamed Chergui, Mohamed Karakellah, Didier Raoult, Philippe Parola Background Argasid ticks (soft ticks) are blood-feeding arthropods that can parasitize rodents, birds, humans, livestock and companion animals. Ticks of the Ornithodoros genus are known to be vectors of relapsing fever borreliosis in humans. In Algeria, little is known about relapsing fever borreliosis and other bacterial pathogens transmitted by argasid ticks

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Conservation of a microRNA cluster in parasitic nematodes and profiling of miRNAs in…

by Henry Y. Gu, Neil D.

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Post-kala-azar dermal leishmaniasis in the Indian subcontinent: A threat to the South-East Asia…

by Eduard E. Zijlstra, Fabiana Alves, Suman Rijal, Byron Arana, Jorge Alvar Background The South-East Asia Region Kala-azar Elimination Programme (KAEP) is expected to enter the consolidation phase in 2017, which focuses on case detection, vector control, and identifying potential sources of infection. Post-kala-azar dermal leishmaniasis (PKDL) is thought to play a role in the recurrence of visceral leishmaniasis (VL)/kala-azar outbreaks, and control of PKDL is among the priorities of the KAEP.

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Zika virus: An updated review of competent or naturally infected mosquitoes

by Yanouk Epelboin, Stanislas Talaga, Loïc Epelboin, Isabelle Dusfour Zika virus (ZIKV) is an arthropod-borne virus (arbovirus) that recently caused outbreaks in the Americas. Over the past 60 years, this virus has been observed circulating among African, Asian, and Pacific Island populations, but little attention has been paid by the scientific community until the discovery that large-scale urban ZIKV outbreaks were associated with neurological complications such as microcephaly and several other neurological malformations in fetuses and newborns.

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Drivers of house invasion by sylvatic Chagas disease vectors in the Amazon-Cerrado transition:…

by Raíssa N. Brito, David E. Gorla, Liléia Diotaiuti, Anália C

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US Gulf Coast states: The rise of neglected tropical diseases in "flyover nation"

by Peter J. Hotez, Sheila Jackson Lee

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Correction: The microbiome in urogenital schistosomiasis and induced bladder pathologies

by Adewale S. Adebayo, Mangesh Survayanshi, Shrikanth Bhute, Atinuke M. Agunloye, Raphael D

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Rapid clearance of <i>Schistosoma mansoni</i> circulating cathodic antigen after…

by Anna O. Kildemoes, Birgitte J. Vennervald, Edridah M.

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Development and validation of an immunoperoxidase antigen detection test for improved diagnosis…

by Ibnu Rahmadane, Andrea F. Certoma, Grantley R.

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Impact of the Ebola outbreak on <i>Trypanosoma brucei gambiense</i> infection…

by Mariame Camara, Eric Ouattara, Alexandre Duvignaud, René Migliani, Oumou Camara, Mamadou Leno, Philippe Solano, Bruno Bucheton, Mamadou Camara, Denis Malvy Background The 2014–2015 Ebola outbreak massively hit Guinea. The coastal districts of Boffa, Dubreka and Forecariah, three major foci of Human African Trypanosomiasis (HAT), were particularly affected.

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Effect of water, sanitation and hygiene interventions on active trachoma in North and South…

by Beselam Tadesse, Alemayehu Worku, Abera Kumie, Solomon Abebe Yimer Background Trachoma is chronic kerato conjunctivitis, which is caused by repeated infection with Chlamydia trachomatis bacterium. It is hyper endemic in many rural areas of Ethiopia. The objective of this study was to measure the effect of water, sanitation and hygiene interventions on active trachoma in selected woredas of North and South Wollo zones of Amhara Region, Ethiopia.

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