Infectious Disease

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Cynthia GoldsmithThis colorized transmission electron micrograph (TEM) revealed some of the ultrastructural morphology displayed by an Ebola virus virion. See PHIL 1832 for a black and white version of this image.Where is Ebola virus found in nature?The exact origin, locations, and natural habitat (known as the "natural reservoir") of Ebola virus remain unknown. However, on the basis of available evidence and the nature of similar viruses, researchers believe that the virus is zoonotic (animal-borne) and is normally maintained in an animal host that is native to the African continent. A similar host is probably associated with Ebola-Reston which was isolated from infected cynomolgous monkeys that were imported to the United States and Italy from the Philippines. The virus is not known to be native to other continents, such as North America.

WHO Failed To Engage Local, International Partners In Ebola Response, Independent Panel Reports

News outlets discuss the first report of the WHO’s Ebola Interim Assessment Panel, released on Monday. Agence France-Presse: Experts denounce WHO’s slow Ebola response “A U.N.-sponsored report on Monday denounced the World Health Organization’s slow response to the Ebola outbreak and said the agency still did not have the capacity to tackle a similar crisis…”…More

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Funding To Address Drug Resistance Requires Public, Private Cooperation, Experts Agree

BBC News: How should the fight against drug resistance be funded? “… ‘Better infection prevention and control in health care settings; a focus on hygiene and sanitation; where appropriate, increasing vaccination uptake,’ says Dr. Charles Penn, the World Health Organization (WHO) coordinator for antimicrobial resistance. All of which would reduce the reliance on antibiotics, he…More

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Prevention of sexually transmitted infections using mobile devices and ubiquitous computing

Background: Advances in the development of information and communication technologies have facilitated social interrelationships, but also sexual contacts without appropriate preventive measures.

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Urbanization of Scrub Typhus Disease in South Korea

by Sang-Won Park, Na-Young Ha, Boyeong Ryu, Ji Hwan Bang, Hoyeon Song, Yuri Kim, Gwanghun Kim, Myoung-don Oh, Nam-Hyuk Cho, Jong-koo Lee Background Scrub typhus is an endemic disease in Asia. It has been a rural disease, but indigenous urban cases have been observed in Seoul, South Korea. Urban scrub typhus may have a significant impact because of the large population


Drivers of Bushmeat Hunting and Perceptions of Zoonoses in Nigerian Hunting Communities

by Sagan Friant, Sarah B. Paige, Tony L. Goldberg Bushmeat hunting threatens biodiversity and increases the risk of zoonotic pathogen transmission.


The Heme Transport Capacity of LHR1 Determines the Extent of Virulence in Leishmania…

by Rebecca L. Renberg, Xiaojing Yuan, Tamika K. Samuel, Danilo C


Identification of sibling species status of Anopheles culicifacies breeding in polluted water…

Background: Anopheles culicifacies s.l., the major vector of malaria in Sri Lanka, is known to breed in clean and clear water.


Nowhere to hide: interrogating different metabolic parameters of Plasmodium falciparum…

Background: The discovery of malaria transmission-blocking compounds is seen as key to malaria elimination strategies and gametocyte-screening platforms are critical filters to identify active molecules.


Biodistribution and Toxicity Studies of PRINT Hydrogel Nanoparticles in Mosquito Larvae and…

by Yashdeep Phanse, Brendan M. Dunphy, Jillian L.


International External Quality Assessment Study for Molecular Detection of Lassa Virus

by Sergejs Nikisins, Toni Rieger, Pranav Patel, Rolf Müller, Stephan Günther, Matthias Niedrig Lassa virus (LASV) is a causative agent of hemorrhagic fever in West Africa. In recent years, it has been imported several times to Europe and North America. The method of choice for early detection of LASV in blood is RT-PCR.


Parasitism in Children Aged Three Years and Under: Relationship between Infection and Growth in…

by A. Desiree LaBeaud, Monica Nayakwadi Singer, Maxim McKibben, Peter Mungai, Eric M. Muchiri, Elisabeth McKibben, Ginny Gildengorin, Laura J


High Rates of Asymptomatic, Sub-microscopic Plasmodium vivax Infection and Disappearing…

by Andreea Waltmann, Andrew W. Darcy, Ivor Harris, Cristian Koepfli, John Lodo, Ventis Vahi, David Piziki, G. Dennis Shanks, Alyssa E


Arterial Hypertension and Skin Allergy Are Risk Factors for Progression from Dengue to Dengue…

by Maria Glória Teixeira, Enny S. Paixão, Maria da Conceição N. Costa, Rivaldo V


Biodistribution and Trafficking of Hydrogel Nanoparticles in Adult Mosquitoes

by Cynthia C. H. Paquette, Yashdeep Phanse, Jillian L.


Malaria and Epstein-Barr Virus: A Lethal Combination

A recent study in PLOS Pathogens investigates how Epstein-Barr virus and malaria co-infection may create a lethal combination if the timing is right. Epstein-Barr virus and malaria are two infections that can each be controlled on their own, but a new study in … Continue reading » The post Malaria and Epstein-Barr Virus: A Lethal Combination appeared first on Speaking of Medicine.


WHO Sends Ebola Response Team To Guinea-Bissau Border Neighboring Recent Cluster In Guinea…

U.N. News Centre: U.N. health agency responds to Ebola spike by deploying team on border of Guinea and Guinea-Bissau “The World Health Organization (WHO) [Wednesday] reported ‘a substantial increase’ in the weekly total of new Ebola cases in Guinea and Sierra Leone and deployed a response team to the border with Guinea-Bissau because of its…More


Despite Global Successes In Malaria Eradication Efforts, Challenges To Prevention, Treatment…

The Guardian: Malaria: can we eradicate one of the world’s deadliest diseases? “…[I]n recent years genuine progress has been made in pushing back against this disease, with an estimated 4.3 million lives saved from malaria since 2001, thanks to a colossal global push. … So how can this be sustained? The places where the disease…More


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