Infectious Disease

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Non Communicable Diseases – A Silent Killer

According to the World Health Organization (WHO), non-communicable diseases (NCDs) represent 46% of the global burden of disease and cause 63% of all deaths in the world, equal to 36 million people per year. Annually nine million people die prematurely before the age of 60 as a result of non-communicable diseases (NCDs). People from developing countries suffer the most: 90% of people who die before the age of 60 are from middle and low-income countries. The World Health Organization estimates that without prevention, 52 million people will die because of NCDs by 2030. As is the case in all developing countries, Uganda is experiencing important changes in disease patterns.

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What Makes Community Engagement Effective?: Lessons from the Eliminate Dengue Program

by Pamela A. Kolopack, Janet A.

Haynes food safety

World Health Day Places Focus On Food Safety, ‘From Farm To Plate’

News outlets report on World Health Day, recognized on April 7. The theme of this year’s day is “From farm to plate, make food safe.” Devex: When one country’s food safety problem becomes a global concern “…The U.N. health agency is scheduled to publish by the fourth quarter of this year a final report providing…More

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Novel pantothenate derivatives for anti-malarial chemotherapy

Background: A number of synthetic pantothenate derivatives, such as pantothenamides, are known to inhibit the growth of the human malaria parasite Plasmodium falciparum, by interfering with the parasite Coenzyme A (CoA) biosynthetic pathway.


Prevalence of K13-propeller polymorphisms in Plasmodium falciparum from China-Myanmar border in…

Background: The recent emergence and spread of artemisinin resistance in the Greater Mekong Subregion poses a great threat to malaria control and elimination.


Using Hospital Discharge Database to Characterize Chagas Disease Evolution in Spain: There Is a…

by Zaida Herrador, Eva Rivas, Alin Gherasim, Diana Gomez-Barroso, Jezabel García, Agustín Benito, Pilar Aparicio After the United States, Spain comes second in the list of countries receiving migrants from Latin America, and, therefore, it is the European country with the highest expected number of infected patients of Chagas disease. We have studied the National Health System’s Hospital Discharge Records Database (CMBD) in order to describe the disease evolution from 1997 to 2011 in Spain. We performed a retrospective descriptive study using CMBD information on hospitalizations including Chagas disease


Correction: A Colour Opponent Model That Explains Tsetse Fly Attraction to Visual Baits and Can…

by Roger D. Santer


Release of Lungworm Larvae from Snails in the Environment: Potential for Alternative…

by Alessio Giannelli, Vito Colella, Francesca Abramo, Rafael Antonio do Nascimento Ramos, Luigi Falsone, Emanuele Brianti, Antonio Varcasia, Filipe Dantas-Torres, Martin Knaus, Mark T. Fox, Domenico Otranto Background Gastropod-borne parasites may cause debilitating clinical conditions in animals and humans following the consumption of infected intermediate or paratenic hosts. However, the ingestion of fresh vegetables contaminated by snail mucus and/or water has also been proposed as a source of the infection for some zoonotic metastrongyloids (e.g., Angiostrongylus cantonensis)


High Prevalence of HTLV-1 Infection among Japanese Immigrants in Non-endemic Area of Brazil

by Larissa M. Bandeira, Silvia N. O.


Trypanosomiasis-Induced Megacolon Illustrates How Myenteric Neurons Modulate the Risk for Colon…

by Vinicius Kannen, Enio C. de Oliveira, Bruno Zene Motta, Annuar Jose Chaguri, Mariângela Ottoboni Brunaldi, Sérgio B. Garcia Background Trypanosomiasis induces a remarkable myenteric neuronal degeneration leading to megacolon


A Recombinant Vesicular Stomatitis Virus-Based Lassa Fever Vaccine Protects Guinea Pigs and…

by David Safronetz, Chad Mire, Kyle Rosenke, Friederike Feldmann, Elaine Haddock, Thomas Geisbert, Heinz Feldmann Background Lassa virus (LASV) is endemic in several West African countries and is the etiological agent of Lassa fever. Despite the high annual incidence and significant morbidity and mortality rates, currently there are no approved vaccines to prevent infection or disease in humans.


Ebola, The Executive Summary: April 17, 2015

To give you an overview of what’s happening in the Ebola outbreak, we’ve organized the latest developments in a curated summary.


In Series Of Interviews, Sierra Leonean President Outlines Ebola Recovery Needs Of West Africa

Reuters: West Africa seeks $5-6 billion aid, debts canceled: Sierra Leone’s Koroma “The Ebola-stricken nations of West Africa are asking international donors to cancel their debts and give them $5-6 billion over two years to rebuild their economies, devastated by the deadly disease, Sierra Leone’s president said on Thursday…” (Dawson, 4/16). VOA News: Sierra Leone…More


U.N., NGO, Multilateral Groups Urge Continued Support For West African Nations Hit Hard By…

CIDRAP News: Multilateral groups to address Ebola economic recovery “With leaders of West African leaders from Ebola-hit nations in Washington, D.C., this week for high-level talks on outbreak recovery, President Barack Obama [Wednesday] urged international partners to stay committed to the fight against the disease and to stand ready to help the nations and their…More


Ebola-Hit Liberia Focuses On Repairing Child Health Care System

Agence France-Presse: Ebola-hit Liberia rebuilds devastated child health care system “…The 46-bed unit [at Liberia’s first ever children’s hospital], just opened in Monrovia by Médecins Sans Frontières (MSF), is part of the country’s response to the challenge of repairing its wrecked health service as it emerges from the nightmare of Ebola. … Liberia is now…More


Researchers Studying Risk Of Sexual Transmission Of Ebola

New York Times: Ebola Researchers Take New Look at Risk of Sexual Transmission “Concerned about the potential for sexual transmission of Ebola, international health officials are investigating new reports of suspected cases and beginning studies to determine how often and how long the virus remains active in semen. And, for now, they are warning Ebola…More


Guinea Confirms 9 New Ebola Cases In Southwest Region

Reuters: Guinea finds nine new Ebola cases near border with Sierra Leone “Guinean authorities have confirmed at least nine new cases of Ebola in the southwest region of Forecariah near the border with Sierra Leone, the area hardest hit by the year-old outbreak, a senior health official said on Thursday…” (Samb, 4/16).


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