Infectious Disease



WHO calls for stronger action on climate-related health risks

Previously unrecognized health benefits could be realized from fast action to reduce climate change and its consequences. For example, changes in energy and transport policies could save millions of lives annually from diseases caused by high levels of air pollution. The right energy and transport policies could also reduce the burden of disease associated with physical inactivity and traffic injury. Measures to adapt to climate change could also save lives around the world by ensuring that communities are better prepared to deal with the impact of heat, extreme weather, infectious disease and food insecurity.


Unprecedented number of medical staff infected with Ebola

The outbreak of Ebola virus disease in west Africa is unprecedented in many ways, including the high proportion of doctors, nurses, and other health care workers who have been infected. To date, more than 240 health care workers have developed the disease in Guinea, Liberia, Nigeria, and Sierra Leone, and more than 120 have died.


Ebola has caused Liberia’s cauldron of dissatisfaction to boil over

Robtel Neajai Pailey | Guardian Development | “Relations between the Liberian state and its citizens were already in crisis before the Ebola outbreak made things Read More


A novel approach for the discovery of chemically diverse anti-malarial compounds targeting the…

Background: Malaria is a devastating parasitic disease, causing more than 600,000 deaths annually.

Severe Plasmodium falciparum infection mimicking acute myocardial infarction

This case report describes a case of presumed acute myocardial infarction in a returned traveler who was later diagnosed to have severe malaria.

Effects of the kdr resistance mutation on the susceptibility of wild Anopheles gambiae…

Background: In the context of generalization of insecticide resistance, the hypothesis that insecticide resistance has a positive impact on the capacity of mosquitoes to transmit malaria constitutes a hindrance for malaria elimination.

Comparing two approaches for estimating the causal effect of behaviour-change communication…

Over the past decade, efforts to increase the use of insecticide-treated bed nets (ITNs) have relied primarily on the routine distribution of bed nets to pregnant women attending antenatal services or on the mass distribution of bed nets to households.

Recent progress in the development of anti-malarial quinolones

Available anti-malarial tools have over the ten-year period, 2002 to 2012, dramatically reduced the number of fatalities attributed to malaria, from one million to less than six-hundred and thirty thousand.

Misunderstanding Of Sex Hinders Effective HIV Prevention Strategies, Experts Say

IRIN: Does the global HIV response understand sex? “Stigma, squeamishness, and misunderstanding of anal sex is leading to research gaps and inaccurate information about the risks of this common sexual behavior, and hindering effective HIV/AIDS prevention strategies, experts say. A move towards ‘sex positive’ approaches could enhance social acceptance and increase protection…” (8/28).

Prevalence and Risk Factors for Echinococcal Infection in a Rural Area of Northern Chile: A…

by Gerardo Acosta-Jamett, Thomas Weitzel, Belgees Boufana, Claudia Adones, Andrea Bahamonde, Katia Abarca, Philip S. Craig, Ingrid Reiter-Owona Background Hydatidosis is a zoonotic disease of worldwide distribution caused by Echinococcus granulosus.

The Prawn Macrobrachium vollenhovenii in the Senegal River Basin: Towards Sustainable…

by Amit Savaya Alkalay, Ohad Rosen, Susanne H. Sokolow, Yacinthe P. W.

Correction: Risk Factors and Spatial Distribution of Schistosoma mansoni Infection among…

by The PLOS Neglected Tropical Diseases Staff

Optimized Multilocus Sequence Typing (MLST) Scheme for Trypanosoma cruzi

by Patricio Diosque, Nicolás Tomasini, Juan José Lauthier, Louisa Alexandra Messenger, María Mercedes Monje Rumi, Paula Gabriela Ragone, Anahí Maitén Alberti-D’Amato, Cecilia Pérez Brandán, Christian Barnabé, Michel Tibayrenc, Michael David Lewis, Martin Stephen Llewellyn, Michael Alexander Miles, Matthew Yeo Trypanosoma cruzi, the aetiological agent of Chagas disease possess extensive genetic diversity. This has led to the development of a plethora of molecular typing methods for the identification of both the known major genetic lineages and for more fine scale characterization of different multilocus genotypes within these major lineages. Whole genome sequencing applied to large sample sizes is not currently viable and multilocus enzyme electrophoresis, the previous gold standard for T.

Non-Participation during Azithromycin Mass Treatment for Trachoma in The Gambia: Heterogeneity…

by Tansy Edwards, Elizabeth Allen, Emma M. Harding-Esch, John Hart, Sarah E.

Viral Aetiology of Central Nervous System Infections in Adults Admitted to a Tertiary Referral…

by Le Van Tan, Le Hong Thai, Nguyen Hoan Phu, Ho Dang Trung Nghia, Ly Van Chuong, Dinh Xuan Sinh, Nguyen Duy Phong, Nguyen Thi Hoang Mai, Dinh Nguyen Huy Man, Vo Minh Hien, Nguyen Thanh Vinh, Jeremy Day, Nguyen Van Vinh Chau, Tran Tinh Hien, Jeremy Farrar, Menno D. de Jong, Guy Thwaites, H. Rogier van Doorn, Tran Thi Hong Chau Background Central nervous system (CNS) infections are important diseases in both children and adults worldwide

A Single Crossing-Over Event in Voltage-Sensitive Na+ Channel Genes May Cause Critical Failure…

by Koichi Hirata, Osamu Komagata, Kentaro Itokawa, Atsushi Yamamoto, Takashi Tomita, Shinji Kasai The voltage-sensitive sodium (Na+) channel (Vssc) is the target site of pyrethroid insecticides. Pest insects develop resistance to this class of insecticide by acquisition of one or multiple amino acid substitution(s) in this channel. In Southeast Asia, two major Vssc types confer pyrethroid resistance in the dengue mosquito vector Aedes aegypti, namely, S989P+V1016G and F1534C

Case Report of Two Cases of Fever, Rash, and Organ Involvement during the Treatment of Leprosy

by Hong Liu, Chuan Wang, Tongsheng Chu, Parimi Leela Rani, Debao Yu, Xi’an Fu, Mingfei Chen, Shumin Chen, Furen Zhang

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