Infectious Disease



Ebola vaccine shows promising results

Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial   Source: Ebola vaccine shows Read More


Accelerating an Integrated Approach to NCD Prevention and Control Globally

Dr. Samira Asma, Chief, Global NCD Program, CDC Over the past 18 years, I’ve worked with Ministries of Health and other partners in 180 countries to advance CDC’s overarching global health goals and accelerate strategies for the prevention and control of noncommunicable diseases (NCDs) and injuries. NCDs and injuries are responsible for millions of premature deaths, especially in low- and middle-income counties (LMICs). As public health practitioners, we have an important opportunity to work collaboratively to accelerate and scale up implementation of proven prevention and treatment strategies and measure their impact.

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Health Aid: Insights From A Review Of Cost-Effectiveness Studies

Health Aid Is Allocated Efficiently, But Not Optimally according to a new review of cost-effectiveness studies published in Health Affairs. Source: Health Aid Is Allocated Efficiently, Read More


The Ebola Vaccine: Seven Things to Understand About rVSV-ZEBOV

A trial of the rVSV-ZEBOV Ebola vaccine among 7,651 individuals in Guinea has been found to have a protection rate of 100 percent. The vaccine was developed by Merck, the Wellcome Trust and the governments of Norway and Canada, in conjunction with MSF and the London School of Hygiene and Tropical Medicine. Public health experts are calling for the vaccine to be rolled out immediately.

Genetic evidence for contribution of human dispersal to the genetic diversity of EBA-175 in…

Background: The 175-kDa erythrocyte binding antigen (EBA-175) of Plasmodium falciparum plays a crucial role in merozoite invasion into human erythrocytes.

Ebola vaccine shows promising results


Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial   Source: Ebola vaccine shows Read More

Modelling the Contributions of Malaria, HIV, Malnutrition and Rainfall to the Decline in…

by Nicholas A. Feasey, Dean Everett, E. Brian Faragher, Arantxa Roca-Feltrer, Arthur Kang’ombe, Brigitte Denis, Marko Kerac, Elizabeth Molyneux, Malcolm Molyneux, Andreas Jahn, Melita A

The Rapid-Heat LAMPellet Method: A Potential Diagnostic Method for Human Urogenital…

by Javier Gandasegui, Pedro Fernández-Soto, Cristina Carranza-Rodríguez, José Luis Pérez-Arellano, Belén Vicente, Julio López-Abán, Antonio Muro Background Urogenital schistosomiasis due to Schistosoma haematobium is a serious underestimated public health problem affecting 112 million people – particularly in sub-Saharan Africa. Microscopic examination of urine samples to detect parasite eggs still remains as definitive diagnosis.

Activity Profile of an FDA-Approved Compound Library against Schistosoma mansoni

by Gordana Panic, Mireille Vargas, Ivan Scandale, Jennifer Keiser Background As plans to expand mass drug treatment campaigns to fight schistosomiasis form, worries about reliance on praziquantel as the sole available treatment motivate the investigation for novel antischistosomal compounds. Drug repurposing might be an inexpensive and effective source of novel antischistosomal leads.

Circulating miRNAs: Potential Novel Biomarkers for Hepatopathology Progression and Diagnosis of…

by Pengfei Cai, Geoffrey N. Gobert, Hong You, Mary Duke, Donald P. McManus Background Schistosomiasis remains a major public health issue, with an estimated 230 million people infected worldwide.

Comparative Phylogenetic Studies on Schistosoma japonicum and Its Snail Intermediate Host…

by Stephen W. Attwood, Motomu Ibaraki, Yasuhide Saitoh, Naoko Nihei, Daniel A. Janies Background Schistosoma japonicum causes major public health problems in China and the Philippines; this parasite, which is transmitted by freshwater snails of the species Oncomelania hupensis, causes the disease intestinal schistosomiasis in humans and cattle.

Levels of 8-OxodG Predict Hepatobiliary Pathology in Opisthorchis viverrini Endemic Settings in…

by Prasert Saichua, Anna Yakovleva, Christine Kamamia, Amar R. Jariwala, Jiraporn Sithithaworn, Banchob Sripa, Paul J.

Fitness and Phenotypic Characterization of Miltefosine-Resistant Leishmania major

by Kimbra G. Turner, Paola Vacchina, Maricela Robles-Murguia, Mariha Wadsworth, Mary Ann McDowell, Miguel A.

Experimental Ebola Vaccine Trial’s Initial Results ‘Promising,’ WHO’s Chan Says Ahead…

Agence France-Presse: Ebola vaccine shows ‘promising’ results: WHO “Preliminary results of tests on an Ebola vaccine to be published in British science magazine The Lancet later Friday have shown ‘promising’ results, World Health Organization Director-General Margaret Chan said…” (7/31). Reuters: WHO’s Chan says initial results from Ebola vaccine trial ‘promising’ “… ‘If proven effective, this…More

More Than 70K Births In Liberia Unrecorded During Ebola Outbreak, Leaving Children Vulnerable…

New York Times: Liberia: Ebola Stalls Birth Registrations “The births of more than 70,000 children in Liberia during the Ebola crisis were never recorded, leaving them vulnerable to marginalization as noncitizens, denial of government services, trafficking, and illegal adoption, UNICEF reported Thursday…” (Gladstone, 7/30). Thomson Reuters Foundation: Ebola disrupts Liberia birth records, poses trafficking threat…More

500 People Under Quarantine In Sierra Leone Village Previously Ebola-Free After Man Dies Of…

Associated Press: Sierra Leone faces Ebola setback; 500 under quarantine “Authorities in Sierra Leone said Thursday they had quarantined 500 people after a man died from Ebola in an area where the deadly virus had been gone for months, in another setback for the fight against the disease…” (Roy-Macaulay, 7/30).

BBC News Profiles Couple That Represents ‘Public Face Of HIV/AIDS In Bhutan’

BBC News: We told the king we had HIV “For the last few years, Wangda Dorje and Tshering Choden have been the public face of HIV/AIDS in Bhutan. They were among a group of five who were the first in the country to come out as HIV-positive — in front of the King, and then…More

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