Infectious Disease


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A Monovalent Chimpanzee Adenovirus Ebola Vaccine — Preliminary Report

In a new report from NEJM, vaccine against EBOV was immunogenic at the doses tested. A Monovalent Chimpanzee Adenovirus Ebola Vaccine — Preliminary Report — Read More


Key Data Points for Guiding the Ebola Response

While the general strategies for Ebola control – community engagement, contact tracing, patient transport, lab diagnosis, and isolation with treatment – are clear, ensuring effective Read More

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Information Systems: the Secret to Solving Uganda’s Health Problems

It’s interesting how so many ideas have been documented and visualized about improving the health sector in Uganda, while ignoring the fact that an improved health sector starts with health providers being able to work more efficiently and effectively. This involves proper documentation of patient records, proper data storage, and proper feedback mechanisms in order to create a smooth information flow. Most of the current processes are often manual and more laborious than they need to be. This causes greater inefficiencies, longer turn-around time, loss of revenue due to inaccurate compilations, inability to archive data for future use, and poor allocation of resources. Well developed health information systems that are based on the idea of sharing critical information can assist areas of operation in the health sector


Development and Validation of a Luminescence-based, Medium-Throughput Assay for Drug Screening…

by Cristiana Lalli, Alessandra Guidi, Nadia Gennari, Sergio Altamura, Alberto Bresciani, Giovina Ruberti Background Schistosomiasis, one of the world’s greatest neglected tropical diseases, is responsible for over 280,000 human deaths per annum. Praziquantel, developed in the 1970s, has high efficacy, excellent tolerability, few and transient side effects, simple administration procedures and competitive cost and it is currently the only recommended drug for treatment of human schistosomiasis. The use of a single drug to treat a population of over 200 million infected people appears particularly alarming when considering the threat of drug resistance

Emergence of a New Lineage of Dengue Virus Type 2 Identified in Travelers Entering Western…

by Timo Ernst, Suzi McCarthy, Glenys Chidlow, Dagwin Luang-Suarkia, Edward C. Holmes, David W. Smith, Allison Imrie Dengue virus (DENV) transmission is ubiquitous throughout the tropics

Classification of Bartonella Strains Associated with Straw-Colored Fruit Bats (Eidolon helvum)…

by Ying Bai, David T. S. Hayman, Clifton D.

Back in Berlin: NTD Discussions Advance

; Last week, the Global Network for Neglected Tropical Diseases and the Sabin Vaccine Institute hosted a well-attended parliamentary workshop in Germany to raise awareness and deepen support for the cause of Neglected Tropical Diseases (NTDs). The event was organized in conjunction with the Global Network’s on-the-ground partners and included presentations from Dr. Lorenzo Savioli, […]

Bold child health goals: worth the gamble

About the guest author For most people, the new year means a bit of champagne, a reason to celebrate, and resolutions about personal changes. For Bill and Melinda Gates, the new year brings their annual letter and thoughts about global issues, world progress, and changes for billions of people. And this new year included a bet: in their annual letter, the Gates’ bet that “the li read more

Ebola, The Executive Summary: January 30, 2015

To give you an overview of what’s happening in the Ebola outbreak, we’ve organized the latest developments in a curated summary.

NIH Still Feeling Budgetary Pinch, As Emergency Ebola Funding Excluded From Federal Spending…

The Lancet: NIH budget shrinks despite Ebola emergency funds “…Congress narrowly approved the US$5.4 billion emergency Ebola funding contained in the $1.1 trillion spending bill that kept the U.S. government running. But so far, it has done little to loosen the budget constraints on the National Institutes of Health (NIH) — even as a global…More

Governments, International Organizations To Work On Plan To Rebuild Ebola-Hit West Africa At…

Reuters: March meeting to plan rebuilding of Ebola-hit states “… ‘The plans at the moment are for a conference to look at the needs of reconstruction organized by the countries themselves, by the United Nations, by the African Union, and by the European Union,’ said David Nabarro, the U.N. special envoy on Ebola. He told…More

Examining Cultural Beliefs, Providing Information Crucial To Successful Anti-Ebola Campaigns

IRIN: Ebola — is culture the real killer? “…What is the value of ‘traditional beliefs’ when they are harmful: why can’t people just act more rationally? The simple answer is: ask the communities. The growing number of researchers that do, find that people are acting as responsibly as they can in desperate circumstances. The lack…More

Shortage Of Sufficiently Trained Personnel Remains Challenge In Ebola-Hit West Africa

Devex: Training health workers yet another challenge in battling Ebola “While the World Health Organization declared this week that the Ebola epidemic has finally reached a ‘turning point,’ international organizations working on the ground are struggling to cope with staffing challenges, including how to train the best foreign and local specialists to treat patients and…More

Underused Ebola Clinics In West Africa Could Be Used For Future Outbreaks

Foreign Policy: An Empty, Underused Medical Outpost Could Be the Future of the Ebola Fight “…U.S.-built [Ebola] treatment centers are sitting mostly empty around [Liberia], prompting criticism that the large international response was too slow to be of any real use in the fight. The facilities could still be of value, though, because they increase…More

Improved Education, Alternative Prevention Methods Can Reduce Malaria Bed Net Misuse

Huffington Post: Education, Follow-up Helps Prevent Bed Net Misuse Rev. Larry Hollon, chief executive of United Methodist Communications “Bed nets intended to prevent malaria are used in fishing communities in Zambia to fish for food, which is sold in the local market, according to a report in the New York Times. … The root of…More

Ebola: “You can’t say we didn’t know,” says a doctor returned from West Africa

“I don’t want to say ‘what has been allowed to occur, so I’ll backtrack, and say, ‘what has occurred’ . . .” Dr. Dan Lucey is an infectious disease physician who teaches about epidemics at Georgetown University, but when he spoke there last week about his experiences treating Ebola patients in Sierra Leone and Liberia […](Read more…)

Regional Preparedness: Could Guinea-Bissau Handle Ebola?

The Ebola outbreak may be waning in West Africa, but just one case in a country with a brittle health structure could cause a surge in infections. Ebola Deeply went behind the scenes in Guinea-Bissau, which shares a border with Guinea, to learn about the level of preparedness there.

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