Infectious Disease

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Republican health plan seen as a major setback for hepatitis C Medicaid patients

Amid a growing hepatitis C epidemic, federal austerity measures seen as a setback to infection control.  By Sony Salzman It’s been nearly 20 years since Read More

Meet the amazing cast behind a life-changing drug

It was well after midnight in San Francisco when Eugenio (“Geno”) de Hostos picked up the phone—but when his colleagues in China answered, he felt the familiar jolt of excitement. He’d felt the same thrill at dawn, talking to his colleagues in Switzerland. At five, in a call to Maryland with the US Food and […] ; ; ; ;Related StoriesWaking from sleeping sickness in the DRCThe surprising consequences of tuberculosisPATH is at SXSW ;

Photo: PATH/Lynn Heinisch.

Lessons from the front lines

In the midst of the 2014 Ebola outbreak in West Africa, a 21-year-old Guinean student came to a Dakar health clinic with symptoms of fever and diarrhea. The doctor considered Ebola, which had killed more than 1,000 people in neighboring Guinea. But the patient wasn’t bleeding. He denied having been in contact with Ebola patients […] ; ; ; ;Related StoriesIn Davos, Rx for epidemics: tech partnershipsInnovation is at the heart of SeattleOur 8 favorite photos of 2016 ;

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<i>Schistosoma japonicum</i> transmission risk maps at present and under climate…

by Gengping Zhu, Jingyu Fan, A. Townsend Peterson Background The South-to-North Water Diversion (SNWD) project is designed to channel fresh water from the Yangtze River north to more industrialized parts of China. An important question is whether future climate change and dispersal via the SNWD may synergistically favor a northward expansion of species involved in hosting and transmitting schistosomiasis in China, specifically the intermediate host, Oncomelania hupensis


Characterization of the Zika virus induced small RNA response in <i>Aedes…

by Margus Varjak, Claire L. Donald, Timothy J. Mottram, Vattipally B.


Impaired anti-fibrotic effect of bone marrow-derived mesenchymal stem cell in a mouse model of…

by Julián Camilo Arango, Juan David Puerta-Arias, Paula Andrea Pino-Tamayo, Lina María Salazar-Peláez, Mauricio Rojas, Ángel González Bone marrow-derived mesenchymal stem cells (BMMSCs) have been consider as a promising therapy in fibrotic diseases. Experimental models suggest that BMMSCs may be used as an alternative therapy to treat chemical- or physical-induced pulmonary fibrosis. We investigated the anti-fibrotic potential of BMMSCs in an experimental model of lung fibrosis by infection with Paracoccidioides brasiliensis


CGD Blog Post Outlines Importance Of Research, Funding To Prepare For Next Ebola Outbreak

Center for Global Development’s “Global Health Policy Blog”: Preparing for the Next Ebola Outbreak: Incentivizing the Right Type of Capacity Kalipso Chalkidou, director of global health policy and senior fellow at CGD, discusses a recent report from the National Academies of Science, Engineering, and Medicine (NASEM) “making the case for ‘Integrating Clinical Research into Epidemic…More


Global challenges of health in the workplace

Over 54% of the world’s population live in urban areas, and over the next decade the growth of cities is expected to be greatest in Africa – the part of the world currently the least covered by workplace health. If we get this right, the potential to improve human wellbeing is vast. Evidence of the effectiveness of workplace health (or ‘wellness’) programmes is often unclear, and in low- and middle-income countries (LMICs) the evidence is particularly thin. I have recently been investigating workplace health in LMICs* – desk research and a series of key informant interviews (India, China, South Africa, Brazil and Argentina) – and, while many of the challenges are problems for workplaces everywhere, they are often more acute in lower-income countries. A 2016 survey of 430 organisations found that the top three workplace-health issues globally are all related to non-communicable diseases (NCDs): poor nutrition, physical inactivity and stress.


Substantial population structure of <i>Plasmodium vivax</i> in Thailand facilitates…

by Veerayuth Kittichai, Cristian Koepfli, Wang Nguitragool, Jetsumon Sattabongkot, Liwang Cui Background Plasmodium vivax transmission in Thailand has been substantially reduced over the past 10 years, yet it remains highly endemic along international borders. Understanding the genetic relationship of residual parasite populations can help track the origins of the parasites that are reintroduced into malaria-free regions within the country. Methodology/Results A total of 127 P


Developing a dengue forecast model using machine learning: A case study in China

by Pi Guo, Tao Liu, Qin Zhang, Li Wang, Jianpeng Xiao, Qingying Zhang, Ganfeng Luo, Zhihao Li, Jianfeng He, Yonghui Zhang, Wenjun Ma Background In China, dengue remains an important public health issue with expanded areas and increased incidence recently. Accurate and timely forecasts of dengue incidence in China are still lacking. We aimed to use the state-of-the-art machine learning algorithms to develop an accurate predictive model of dengue


Rapid Test To Diagnose Malaria Shows Shortcomings In Real-World Setting, Study Says

PRI: With quick and easy malaria tests, some unexpected drawbacks “…The [rapid] test can diagnose malaria in 15 minutes with just the prick of a finger — making it easier to prescribe anti-malarial drugs only when they’re needed, and slowing the rise of drug-resistant malaria strains. But according to a recent study published in the…More


NIH Official Discusses Need To Issue Exclusive License To Drug Company For Zika Vaccine…

CQ HealthBeat: NIH Tries to Ease Concerns About Zika Vaccine Deal “The federal government is considering granting a pharmaceutical company an exclusive license to further develop a taxpayer-funded vaccine for the Zika virus, just weeks after a similar arrangement was scuttled following blowback from health groups and lawmakers. … In a pair of conference calls…More


Studies Show Shorter, Less Toxic Drug Combinations Could Be Effective In Treating…

Devex: 3 innovations that could transform TB diagnosis and care “Ending global tuberculosis will require new diagnostic tools, new ways to support adherence to treatment, new drug regimens, and a vaccine, experts told Devex at the 48th Union World Conference on Lung Health. … Experts including those gathered in Guadalajara this week are working tirelessly…More


Malaria risk factors and care-seeking behaviour within the private sector among high-risk…

Vietnam has successfully reduced malaria incidence by more than 90% over the past 10 years, and is now preparing for malaria elimination.


High prevalence of very-low Plasmodium falciparum and Plasmodium vivax parasitaemia carriers in…

The incidence of malaria due both to Plasmodium falciparum and Plasmodium vivax in the Peruvian Amazon has risen in the past 5 years.


A recombinase polymerase amplification assay for rapid detection of Crimean-Congo Haemorrhagic…

by Laura C. Bonney, Robert J.


Clinico-pathological features of erythema nodosum leprosum: A case-control study at ALERT…

by Edessa Negera, Stephen L. Walker, Selfu Girma, Shimelis N. Doni, Degafe Tsegaye, Saba M.


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