Diahrreal Disease


Controversy over transparency: why non-profits need to disclose their “real” overhead ratio

“The fact is an average of 91 cents of every dollar the Red Cross spends is invested in our humanitarian services and programs.”[1] This is Read More

Reflections on a year of malnutrition

Malnutrition is frustrating. I often sit in the office, analyzing data from our programs, and feel helpless. Children who stay the same height for two Read More

Links between child and adult chronic diseases: Lessons from Guatemala

Since 2013, I have had the great joy of working in rural Guatemala for the non-governmental organization Wuqu’ Kawoq | Maya Health Alliance—first during medical Read More


Diarrhea, the time thief

Diarrhea, the time thief hrandall Mon, 02/12/2018 – 10:56 Feb 12, 2018 Thomas Wierzba Senior Scientist, PATH’s Center for Vaccine Development and Access (CVIA) A child in Sudan receives ORS during a hospital stay for severe diarrhea. PATH/Doune Porter.   Global deaths from diarrhea are falling, rapidly. This is encouraging news—it means that fewer parents are living with the tragedy of a child lost to diarrhea.

If childhood stunting is a three-legged stool, poor gut health is one leg

If childhood stunting is a three-legged stool, poor gut health is one leg hrandall Wed, 02/07/2018 – 16:42 Feb 07, 2018 defeatDD Dr. Mark Manary, one of the world’s foremost experts in childhood malnutrition, screens children in Chikweo, Malawi. Photo: Carol Lin.   With 155 million stunted children in the world, progress against the complex condition is not coming fast enough to meet the 40 percent reduction target set by the United Nations Sustainable Development Goals. We spoke to Dr.

icddr,b launches a preemptive strike against cholera with vaccines

icddr,b launches a preemptive strike against cholera with vaccines hrandall Thu, 02/01/2018 – 10:44 Feb 01, 2018 Farasha Bashir Communications Specialist, icddr,b The emergency The Rohingyas are a predominantly Muslim ethnic group who, for centuries, resided in the Buddhist-dominant Rakhine State of Myanmar. However, they are not considered by Myanmar as one of their 135 official ethnic groups and have been denied citizenship since 1982, effectively rendering them stateless.   In August 2017, thousands of Forcibly Displaced Myanmar Nationals (FDMN) fled from Myanmar due to a violent military crackdown. More than 625,000 FDMNs arrived in Cox’s Bazar, the border district of Bangladesh, in what the UN has called the most urgent refugee emergency in the world.     Limited space in registered camps created a vast challenge for Bangladesh where FDMNs have set up ‘home’ in informal shanties made from polythene and bamboo sticks.

Ringing in 2018 with an exciting rotavirus vaccine milestone

Ringing in 2018 with an exciting rotavirus vaccine milestone hrandall Tue, 01/23/2018 – 16:53 Jan 24, 2018 Allison Clifford Communications Officer for the Vaccine Development program at PATH Rotavirus vaccines are starting off the new year with a bang! Bharat Biotech just announced that ROTAVAC® has achieved prequalification by the World Health Organization (WHO), making it available for procurement by United Nations agencies and Gavi, the Vaccine Alliance, for use in low-resource countries. This marks the first new rotavirus vaccine to achieve WHO prequalification since 2009, bringing a new affordable option to the table for low-resource countries.   Rotavirus is the most common cause of severe diarrheal disease in children worldwide, and vaccines are the best way to prevent this terrible illness. Although more than 90 countries have already introduced rotavirus vaccines into their national immunization programs, 67 percent of all children—more than 90 million infants—still lack access to rotavirus vaccines

Join PATH in Mexico City for the next VASE Conference!

Join PATH in Mexico City for the next VASE Conference! hrandall Tue, 01/09/2018 – 16:06 Jan 09, 2018 Dr. Richard Walker Director of PATH’s enteric vaccine project Nearly two years ago, I announced PATH’s first international Vaccines Against Shigella and enterotoxigenic Escherichia coli (ETEC) Conference (more commonly known as the VASE Conference), and I blogged about our high hopes and exciting plans for the event. This meeting was the first of its kind, and we really weren’t sure what to expect.

Going straight to the source for vaccine research

Going straight to the source for vaccine research hrandall Wed, 01/03/2018 – 12:50 Jan 03, 2018 Study team Helsinki University Hospital You might be more used to seeing the shorthand abbreviation for ETEC, one of the leading bacterial causes of diarrhea. The 13-syllable mouthful is a lot to digest: Enterotoxigenic Escherichia coli. I can tell you that it is a mouthful in Finnish, too.   There is currently no vaccine against ETEC, and we’re working to change that. While a vaccine to protect against ETEC would be welcome news to globetrotters who want protection against traveler’s diarrhea, our objective in researching this vaccine is to prevent death and disability in children that ETEC causes, primarily in poor settings.

DefeatDD’s top ten in 2017

DefeatDD’s top ten in 2017 hrandall Tue, 12/26/2017 – 15:29 Dec 26, 2017 defeatDD Our Toilet Talks campaign was not a blog per se, but it was a major 2017 moment. Check out our new case study summarizing the highlights.   Perhaps you can sense the collective exhale as global health sector news slows for the holiday season. As usual, it’s our favorite time to dig into the analytics and check out your favorite DefeatDD blog posts of the year, always a fun and illuminating activity. This year in particular, it was like looking through a scrapbook of our many 2017 product launches

A tale of holiday woe

A tale of holiday woe hrandall Wed, 12/20/2017 – 23:29 Dec 20, 2017 Laura Edison Kallen Scientific Communications Associate, PATH You know what makes for a really memorable holiday?   Viral diarrhea.   This year, a few days before my family was due to arrive at my parents’ house for Thanksgiving, my mom came down with a very mild case of stomach flu. She recovered within a day, and she thought it may have just been something she ate.   My family is well aware of the dangers of diarrheal disease—my dad is a gastroenterologist, my mom and older sister are pharmacists, my younger sister is a nurse, and I had been hospitalized with rotavirus as a toddler and now work on diarrheal vaccines at PATH—so naturally we were all concerned about the potential of this illness spreading to others.

The world’s worst cholera outbreak highlights need for long-term solutions

The world’s worst cholera outbreak highlights need for long-term solutions hrandall Fri, 12/01/2017 – 10:08 Dec 01, 2017 Farasha Bashir Communications Specialist, icddr,b In 2015, civil war broke out in Yemen between the government and the rebel movement, triggering a humanitarian crisis that has resulted in more than 70 per cent of the population needing immediate aid and assistance. Yemen is one of the poorest countries in the Arab peninsula, and constant bombings have devastated infrastructure, including roads and hospitals.   One of the most devastating consequences of this war and instability has been the worst cholera outbreak ever recorded. Cholera is an acute diarrhoeal disease that thrives in disadvantaged and unstable environments; it can kill within hours if left untreated. Malnutrition and poor sanitation have made the country vulnerable to cholera, and more than 800,000 civilians have already been affected.

An interview with Raya

An interview with Raya hrandall Thu, 11/16/2017 – 12:49 Nov 16, 2017 Hope Randall Digital Communications Officer for DefeatDD Our team has made so many good friends this year at Sesame Workshop India, both of the human and Muppet variety. We celebrated World Water Day with Chamki and Googly, and now we’re gearing up for World Toilet Day with Raya, who is just as passionate as we are about keeping germs at bay.   We sat down to thank her for contributing a Toilet Talk for our campaign to raise awareness about diarrhea prevention and treatment ahead of World Toilet Day and to share with advocates our new state of the field report. And of course, we continued to talk toilets!   Hope: Good to meet you, Raya

Killing two bugs with one strategy

Killing two bugs with one strategy hrandall Fri, 11/10/2017 – 11:47 Nov 10, 2017 Laura Kallen Senior Scientific Communications Associate, PATH If pneumonia and diarrhea—the two biggest infectious killers of children worldwide—were personified as serial killers, I imagine that they would look very different. Pneumonia might be tall and spindly, with long, wispy fingers. Diarrhea, on the other hand, would be stocky, thick, and very ugly, a grisly force. Both are horrifying to imagine, but then again, so is the reality. These diseases take 1.5 million young lives every year

Coming soon: DefeatDD’s new state-of-the-field report

Coming soon: DefeatDD’s new state-of-the-field report hrandall Tue, 10/31/2017 – 14:58 Nov 01, 2017 Hope Randall Digital Communications Officer for DefeatDD In April 2009 (can’t believe it was eight years ago!), my first task as a newly minted member of PATH’s Poo Crew was to help finalize and launch our team’s first-ever state of the field report on diarrhea: Diarrheal Disease: Solutions to Defeat a Global Killer. I also helped to collect the names of more than 100 organizations from around the world that signed onto a Call to Action statement advocating for greater attention to, and urgency around, diarrheal disease.   As we’d hoped, so much content in those pages is outdated thanks to global progress.. In those early materials, we said things like “Rotavirus vaccines may soon be available for global use.” In late 2009, the World Health Organization issued its recommendation for all countries introduce rotavirus vaccines into their national immunization programs, a key step for vaccine procurement through structures like UNICEF and Gavi, the Vaccine Alliance.

Rotavirus vaccines: a lifesaving opportunity for Afghanistan

Rotavirus vaccines: a lifesaving opportunity for Afghanistan hrandall Tue, 10/31/2017 – 11:17 Oct 31, 2017 Dr. Palwasha Anwari Photo: Palwasha Anwari   Diarrheal disease has haunted Afghanistan for far too long. In 2015, a Demographic and Health Survey from Afghanistan found that, in the two weeks before the survey, nearly three in ten children under five had suffered from diarrhea. It is estimated that more than 45 percent of all diarrhea-related hospitalizations in Afghanistan are due to rotavirus—the leading, deadliest form of severe diarrheal disease—and Afghanistan is one of just ten countries that account for almost two-thirds of all rotavirus deaths worldwide.   This needs to end.

Women lead the way to a healthier India

Women lead the way to a healthier India hrandall Wed, 10/25/2017 – 15:05 Oct 25, 2017 Erika Amaya Digital Communications Officer, PATH On DefeatDD’s trip to India earlier this year, I had the opportunity to meet with many dedicated colleagues working to reduce the toll of childhood diarrhea. As they guided our team through some of the communities most affected by a high burden of infectious disease,  residents shared  their challenges, successes, and hopes for the future.   Through these conversations, I learned that here, women are leading the charge for social change and health.   As our colleague Dr.

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