Malaria

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“Access to information literally saves lives”: free access to UpToDate in LMICs

This week, Yannis Valtis joined us for a short conversation about a new paper he and colleagues recently published in BMJ Global Health. Their study Read More

Malaria burden and costs of intensified control in Bhutan, 2006–14: an…

The malaria burden in Bhutan decreased significantly during the study period with high coverage of long-lasting insecticidal nets. The foreseeable challenges that require national attention to maintain a malaria-free status after elimination are importation of malaria, especially from India; continued protection of the population in endemic districts through complete coverage with long-lasting insecticidal nets and indoor residual spraying; and exploration of local funding modalities post-elimination in the event of a reduction in international funding.

Lifting the Patent Barrier to New Drugs and Energy Sources – The New York Times

Strict patents on technology have had the effect of hindering global progress in some fields, especially in combating disease and climate change. Source: Lifting the Read More

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World Tuberculosis Day: United We Can End TB and Tropical Diseases

The theme of World TB Day is to Unite to end TB: leave no one behind. The communities affected by TB are also ones where tropical diseases like onchocerciasis and malaria are endemic. A successful strategy to control one disease should ideally be “united” with all basic primary health care interventions, thereby truly leaving no one behind. While the causative agents differ between TB and tropical diseases such as malaria, lymphatic filariasis and Dengue, control of these diseases shares a common goal – “an urgent need to develop new vaccines for HIV/AIDS, malaria, and tuberculosis, as well as for respiratory syncytial virus and those chronic and debilitating (mostly parasitic) infections known as neglected tropical diseases (NTDs).” In addition to prevention, there is also need for integrated “treatment pipelines directed at NTDs, Malaria, tuberculosis (TB), and human immunodeficiency virus (HIV)/AIDS,” according to Asada. There is also a need for integrated primary health care (PHC) programming


Analytical sensitivity of current best-in-class malaria rapid diagnostic tests

Rapid diagnostic tests (RDTs) are today the most widely used method for malaria diagnosis and are recommended, alongside microscopy, for the confirmation of suspected cases before the administration of anti-ma…


World Water Day: Water and Neglected Tropical Diseases

The United Nations introduces us to the challenges of water. “Water is the essential  building block of life. But it is more than just essential to quench thirst or protect health; water is vital for creating jobs and supporting economic, social, and human development.” Unfortunately, “Today, there are over 663 million people living without a safe water supply close to home, spending countless hours queuing or trekking to distant sources, and coping with the health impacts of using contaminated water.” Haiti: Importance of Water to prevent STH Many of the infectious health challenges known as Neglected Tropical Diseases (NTDs) have issues of water associated with their transmission. This may relate to scarcity of water and subsequent hygiene problems. It may relate to water quality and contamination


Diagnostic challenges and case management of the first imported case of Plasmodium knowlesi in…

Sri Lanka has achieved ‘malaria-free’ status and is now in the phase of prevention of re-introduction of malaria.


An assessment of national surveillance systems for malaria elimination in the Asia Pacific

Heads of Government from Asia and the Pacific have committed to a malaria-free region by 2030.


Drug resistance mediating Plasmodium falciparum polymorphisms and clinical presentations of…

Plasmodium falciparum genetic polymorphisms that mediate altered drug sensitivity may impact upon virulence.


El Niño Southern Oscillation as an early warning tool for malaria outbreaks in India

Risks of malaria epidemics in relation to El Niño and Southern Oscillation (ENSO) events have been mapped and studied at global level.


False-negative malaria rapid diagnostic tests in Rwanda: impact of Plasmodium falciparum…

Rapid diagnostic tests (RDTs) for histidine rich protein 2 (HRP2) are often used to determine whether persons with fever should be treated with anti-malarials.


Age and geographic patterns of Plasmodium falciparum malaria infection in a representative…

Falciparum malaria is an important risk factor for African Burkitt lymphoma (BL), but few studies have evaluated malaria patterns in healthy BL-age children in populations where both diseases are endemic.


Tryptophan-rich domains of Plasmodium falciparum SURFIN4.2 and Plasmodium vivax PvSTP2 interact…

Plasmodium falciparum dramatically alters the morphology and properties of the infected red blood cells (iRBCs).


Our Patients Will Die Without Foreign Aid

Jodanie Louis holds her son, Lovenyou, outside their home in Boucan-Carré, Haiti. Lovenyou has gone from severely to moderately malnourished under PIH’s malnutrition program.Photo by Cecille Joan Avila / Partners In Health Partners In Health is gravely concerned about deep and significant cuts in United States overseas development assistance in the budget proposed by President Donald J. Trump. As much of this aid is for health in some of the world’s poorest countries, these cuts will have a devastating impact on millions of people throughout the world.


Erratum to: Pre-travel malaria chemoprophylaxis counselling in a public travel medicine clinic…

View original: Erratum to: Pre-travel malaria chemoprophylaxis counselling in a public travel medicine clinic…


Clinical and molecular surveillance of drug resistant vivax malaria in Myanmar (2009–2016)

One of the major challenges for control and elimination of malaria is ongoing spread and emergence of drug resistance.


Confirmation of Plasmodium falciparum in vitro resistance to monodesethylamodiaquine and…

In response to increasing resistance to anti-malarial drugs, Senegal adopted artemisinin-based combination therapy (ACT) as the first-line treatment for uncomplicated malaria in 2006.


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