Malaria

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Communication Challenges: Malaria or Ebola

The purpose of health education of behavior change communication (BCC) is to share ideas such that all sides of the communication process learn to act in ways that better control and prevent disease and promote health.  Both community members (clients) and health workers (providers) need to change behavior is their interaction to become a health promoting dialogue. This dialogue becomes easier when all parties share some common perceptions about the issue at hand. Both health workers and community members can usually agree that malaria often presents with high body temperature. Also both usually agree that malaria can be disruptive of daily life and even be deadly. But there are differences.

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Prevention or Cure, What’s the Best Approach to Malaria Control?

The Malaria Consortium and the Guardian are hosting a Q&A event about approaches to malaria control.  Is it better to focus on prevention or cure? Read More

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Ebola outbreak spreads to Senegal

September 2, 2014 Senegalese authorities on Monday were monitoring everyone who was in contact with

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Marketing approval for UMT from the Nigeria NAFDAC

Fyodor Biotechnologies Inc. has sponsored a study to evaluate the clinical performance of the one-step Fyodor Urine Malaria Test (UMT), to determine its accuracy (sensitivity and specificity) for the diagnosis of Plasmodium falciparum malaria in febrile patients. A total of 1500 properly consented children and adults presenting with fever (axillary temperature ?37.5°C) or history of fever in the last 48 hours (Group 1), 250 apparently “healthy” individuals (Control, Group 2), and 50 patients with Schistosoma hematobium and Rheumatoid arthritis (Group 3), were recruited. Matched urine and fingerprick (capillary) blood samples were collected and tested using the UMT and, Binax NOW® malaria rapid diagnostic test (blood test) and thick smear microscopy, respectively.


New York Times Profiles PMI Coordinator Rear Adm. Timothy Ziemer

New York Times: The Malaria Fighter “…Since [Rear Admiral Timothy Ziemer] took the job [as coordinator of the President's Malaria Initiative] in 2006, worldwide malaria deaths have dropped 40 percent, to about 600,000 a year from one million. … Many countries now use the tactics Admiral Ziemer adopted after demanding proof that they worked. For…More


Efficacy of intravenous methylene blue, intravenous artesunate, and their combination in…

Background: Intravenous artesunate (IV AS) is the present treatment of choice for severe malaria, but development of artemisinin resistance indicates that a further agent will be needed.


In vitro and in vivo anti-malarial activity of tigecycline, a glycylcycline antibiotic, in…

Background: Several antibiotics have shown promising anti-malarial effects and have been useful for malarial chemotherapy, particularly in combination with standard anti-malarial drugs.


Malaria parasite detection increases during pregnancy in wild chimpanzees

Background: The diversity of malaria parasites (Plasmodium sp.) infecting chimpanzees (Pan troglodytes) and their close relatedness with those infecting humans is well documented.


High-throughput tri-colour flow cytometry technique to assess Plasmodium falciparum…

Background: Unbiased flow cytometry-based methods have become the technique of choice in many laboratories for high-throughput, accurate assessments of malaria parasites in bioassays.


Detection of mixed infection level of Plasmodium falciparum and Plasmodium vivax by SYBR Green…

Background: Malaria is caused by five Plasmodium species and transmitted by anopheline mosquitoes.


Nationwide assessment of insecticide susceptibility in Anopheles gambiae populations from…

Background: The scale-up of malaria interventions in sub-Saharan Africa has been accompanied by a dramatic increase in insecticide resistance in Anopheles spp.


Comparative analysis of IgG responses to Plasmodium falciparum MSP1p19 and PF13-DBL1alpha1…

Background: Numerous Plasmodium falciparum antigens elicit humoral responses in humans living in endemic areas.


Anti-relapse activity of mirincamycin in the Plasmodium cynomolgi sporozoite-infected Rhesus…

Background: Mirincamycin is a close analog of the drug clindamycin used to treat Plasmodium falciparum blood stages.


Enantiomerically pure amino-alcohol quinolines: in vitro anti-malarial activity in combination…

Background: As resistance to marketed anti-malarial drugs continues to spread, the need for new molecules active on Plasmodium falciparum-resistant strains grows.


Genetic mutations in pfcrt and pfmdr1 at the time of artemisinin combination therapy…

Background: Chloroquine (CQ), alone or in combination with sulphadoxine-pyrimethamine, was widely used for the treatment of Plasmodium falciparum and Plasmodium vivax for several decades in both Vanuatu and Solomon Islands prior to the introduction of artemether-lumefantrine (AL) in 2008.


Clinical malaria case definition and malaria attributable fraction in the highlands of western…

Background: In African highland areas where endemicity of malaria varies greatly according to altitude and topography, parasitaemia accompanied by fever may not be sufficient to define an episode of clinical malaria in endemic areas.


A descriptive study of 16 severe Plasmodium vivax cases from three municipalities of Colombia…

Background: Plasmodium vivax, the most geographically distributed cause of malaria, accounts for more than 70% of cases in the Americas.


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