Neglected Tropical Diseases



Insecticidal Paints: A Realistic Approach to Vector Control?

by Karin L. Schiøler, Michael Alifrangis, Uriel Kitron, Flemming Konradsen


News in the Humanosphere: Angola suffers worst Yellow Fever outbreak in 30 years

Angola is grappling with a yellow fever outbreak, which has infected more than 450 people and killed 178 – the first epidemic of the disease to hit the country in 30 years. The outbreak, which was first reported in the capital city Luanda in December 2015, has since spread to 6 of the country’s 18


View on Poverty: Rift Valley fever fight is flawed

Unexplained meat bans can alienate people and hurt livelihoods. Salome Bukachi proposes ways to improve response.


Syrian Civil War Allows Cutaneous Leishmaniasis Outbreak To Take Hold

NPR: ‘The Aleppo Evil’ Is Making A Comeback “…The disease, now known as Old World cutaneous leishmaniasis, or CL, is not unique to Syria. It’s found in parts of the Middle East, Africa, Asia, and southern Europe, according to the Centers for Disease Control. But ever since Syria’s civil war started in 2011, what had…More

Southern Europe’s Coming Plagues: Vector-Borne Neglected Tropical Diseases

by Peter J. Hotez

Rapid and Non-destructive Detection and Identification of Two Strains of…

by Maggy T. Sikulu-Lord, Marta F. Maia, Masabho P.

Optimization of a Membrane Feeding Assay for <i>Plasmodium vivax</i> Infection in…

by Andrés F. Vallejo, Kelly Rubiano, Andres Amado, Amy R. Krystosik, Sócrates Herrera, Myriam Arévalo-Herrera Introduction Individuals exposed to malaria infections for a long time develop immune responses capable of blocking Plasmodium transmission to mosquito vectors, potentially limiting parasite spreading in nature.

Performance Testing of PCR Assay in Blood Samples for the Diagnosis of Toxoplasmic Encephalitis…

by Daniel Ajzenberg, Isabelle Lamaury, Magalie Demar, Cyrille Vautrin, André Cabié, Stéphane Simon, Muriel Nicolas, Nicole Desbois-Nogard, Rachida Boukhari, Homayoun Riahi, Marie-Laure Dardé, Patrice Massip, Michel Dupon, Pierre-Marie Preux, Anaïs Labrunie, Marie-Paule Boncoeur Background Toxoplasmic encephalitis in patients with AIDS is a life-threatening disease mostly due to reactivation of Toxoplasma gondii cysts in the brain. The main objective of this study was to evaluate the performance of real-time PCR assay in peripheral blood samples for the diagnosis of toxoplasmic encephalitis in AIDS patients in the French West Indies and Guiana.

Antibody-Mediated Neutralization of the Exotoxin Mycolactone, the Main Virulence Factor…

by Jean-Pierre Dangy, Nicole Scherr, Philipp Gersbach, Melanie N. Hug, Raphael Bieri, Claudio Bomio, Jun Li, Sylwia Huber, Karl-Heinz Altmann, Gerd Pluschke Background Mycolactone, the macrolide exotoxin produced by Mycobacterium ulcerans, causes extensive tissue destruction by inducing apoptosis of host cells.

Concomitant Immunity Induced by Persistent <i>Leishmania major</i> Does Not…

by Michael A. Mandell, Stephen M. Beverley Background Many microbes have evolved the ability to co-exist for long periods of time within other species in the absence of overt pathology

HMGB1 Is a Potential Biomarker for Severe Viral Hemorrhagic Fevers

by Katarina Resman Rus, Luka Fajs, Miša Korva, Tatjana Avšič-Županc Hemorrhagic fever with renal syndrome (HFRS) and Crimean-Congo hemorrhagic fever (CCHF) are common representatives of viral hemorrhagic fevers still often neglected in some parts of the world. Infection with Dobrava or Puumala virus (HFRS) and Crimean-Congo hemorrhagic fever virus (CCHFV) can result in a mild, nonspecific febrile illness or as a severe disease with hemorrhaging and high fatality rate.

Clonorchis sinensis Co-infection Could Affect the Disease State and…

by Wenfang Li, Huimin Dong, Yan Huang, Tingjin Chen, Xiangzhan Kong, Hengchang Sun, Xinbing Yu, Jin Xu Background Clonorchis sinensis (C. sinensis) is considered to be an important parasitic zoonosis because it infects approximately 35 million people, while approximately 15 million were distributed in China.

Evaluation of syndromic management guidelines for treatment of sexually transmitted infections…

Objective To evaluate the performance of three different guidelines for the management of vaginal discharge syndrome (VDS) for women living in a rural setting in South Africa.

Accuracy of Mobile Phone and Handheld Light Microscopy for the Diagnosis of Schistosomiasis and…

by Jean T. Coulibaly, Mamadou Ouattara, Michael V. D’Ambrosio, Daniel A

The Prevalence of Scabies and Impetigo in the Solomon Islands: A Population-Based Survey

by Daniel S. Mason, Michael Marks, Oliver Sokana, Anthony W. Solomon, David C.

Evolution of the Transmission-Blocking Vaccine Candidates Pvs28 and Pvs25 in…

by Ricardo A. Chaurio, M.

The Schistosomiasis Clinical Trials Landscape: A Systematic Review of Antischistosomal…

by Amélie M. Julé, Michel Vaillant, Trudie A. Lang, Philippe J.

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