Neglected Tropical Diseases

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Are partnerships the key to making critical progress in Global Health?

When it comes to Global Health, there are a number of challenges that the global health community should be aware of and focused on. Many Read More

Meet the amazing cast behind a life-changing drug

It was well after midnight in San Francisco when Eugenio (“Geno”) de Hostos picked up the phone—but when his colleagues in China answered, he felt the familiar jolt of excitement. He’d felt the same thrill at dawn, talking to his colleagues in Switzerland. At five, in a call to Maryland with the US Food and […] ; ; ; ;Related StoriesWaking from sleeping sickness in the DRCThe surprising consequences of tuberculosisPATH is at SXSW ;

Insecticidal Paints: A Realistic Approach to Vector Control?

by Karin L. Schiøler, Michael Alifrangis, Uriel Kitron, Flemming Konradsen

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Analysis of the efficacy of Taiwanese freeze-dried neurotoxic antivenom against <i>Naja…

by Chien-Chun Liu, Chen-Hsien You, Po-Jung Wang, Jau-Song Yu, Guo-Jen Huang, Chien-Hsin Liu, Wen-Chin Hsieh, Chih-Chuan Lin In Southeast Asia, envenoming resulting from cobra snakebites is an important public health issue in many regions, and antivenom therapy is the standard treatment for the snakebite. Because these cobras share a close evolutionary history, the amino acid sequences of major venom components in different snakes are very similar.


Genotyping of <i>Mycobacterium leprae</i> for better understanding of leprosy…

by Amanda N. B.


NTD Progress Report Shows Numbers Of People Affected By Diseases Down, 1B People Received…

Los Angeles Times: Guinea worm, river blindness and elephantiasis are among the world’s neglected tropical diseases. A battle is on to wipe them out “…[T]he combined efforts of governments, nonprofit organizations, academia, and the private sector have helped combat neglected tropical diseases, or NTDs, during the last five years, according to a report published Thursday…More


Polypyridylruthenium(II) complexes exert anti-schistosome activity and inhibit parasite…

by Madhu K. Sundaraneedi, Bemnet Tedla, Ramon M. Eichenberger, Luke Becker, Darren Pickering, Michael J.


Virulence, pathology, and pathogenesis of Pteropine orthoreovirus (PRV) in BALB/c mice:…

by Kazutaka Egawa, Masayuki Shimojima, Satoshi Taniguchi, Noriyo Nagata, Hideki Tani, Tomoki Yoshikawa, Takeshi Kurosu, Shumpei Watanabe, Shuetsu Fukushi, Masayuki Saijo Background Cases of acute respiratory tract infection caused by Pteropine orthoreovirus (PRV) of the genus Orthoreovirus (family: Reoviridae) have been reported in Southeast Asia, where it was isolated from humans and bats. It is possible that PRV-associated respiratory infections might be prevalent in Southeast Asia.


Drug resistance and treatment failure in leishmaniasis: A 21st century challenge

by Alicia Ponte-Sucre, Francisco Gamarro, Jean-Claude Dujardin, Michael P. Barrett, Rogelio López-Vélez, Raquel García-Hernández, Andrew W. Pountain, Roy Mwenechanya, Barbara Papadopoulou Reevaluation of treatment guidelines for Old and New World leishmaniasis is urgently needed on a global basis because treatment failure is an increasing problem.


Emergence of melioidosis in the Indian Ocean region: Two new cases and a literature review

by Nicolas Allou, Olivier Martinet, Jérôme Allyn, Bruno Bouchet, Marie-Christine Jaffar-Bandjee, Thomas Galas, Nicolas Traversier, Olivier Belmonte Author summary: Melioidosis is a disease caused by bacteria called B. pseudomallei.


RNA interference in <i>Fasciola gigantica</i>: Establishing and optimization of…

by Arun Anandanarayanan, Opinder Krishen Raina, Hniang Lalrinkima, Ajayta Rialch, Muthu Sankar, Anju Varghese Fasciolosis caused by Fasciola gigantica is a neglected tropical disease but a constraint on the growth and productivity of cattle, buffaloes and sheep in the tropical countries of Asia and Africa. Resistance to commonly used anthelmintics in Fasciola has increased the need to search for alternative therapeutic targets.


Elimination of trachoma as a public health problem in Ghana: Providing evidence through a…

by Oscar Debrah, Ernest O. Mensah, Laura Senyonjo, Dziedzom K. de Souza, Tei E


Trachomatous scarring among children in a formerly hyper-endemic district of Tanzania

by Jacob T. Cox, Harran Mkocha, Beatriz Munoz, Sheila K. West Background Associations between repeated ocular infections with Chlamydia trachomatis in childhood and conjunctival scarring in adulthood are well established.


Sustaining visceral leishmaniasis elimination in Bangladesh – Could a policy brief help?

by Alyssa Fitzpatrick, Noor Saad M. S. Al-Kobaisi, Jessica Beitman Maya, Yu Ren Chung, Satyender Duhan, Erdene Elbegdorj, Sushant Jain, Edward Kuhn, Alexandra Nastase, Be-Nazir Ahmed, Piero Olliaro Bangladesh has made significant progress towards elimination of visceral leishmaniasis, and is on track to achieve its target of less than one case per 10,000 inhabitants in each subdistrict in 2017.


Prices For Medications To Treat NTDs Often Inflated In U.S.

NPR: Why A Pill That’s 4 Cents In Tanzania Costs Up To $400 In The U.S. “…Drugs for diseases of the developing world, in particular what are known as ‘neglected tropical diseases’ like hookworm and leishmaniasis, are enormously more expensive in the United States than in the developing world. ‘There really is no good reason…More


Low cost, low tech SNP genotyping tools for resource-limited areas: Plague in Madagascar as a…

by Cedar L. Mitchell, Voahangy Andrianaivoarimanana, Rebecca E.


Characterization of the <i>Giardia intestinalis</i> secretome during interaction…

by Showgy Y. Ma’ayeh, Jingyi Liu, Dimitra Peirasmaki, Katarina Hörnaeus, Sara Bergström Lind, Manfred Grabherr, Jonas Bergquist, Staffan G.


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