by Karin L. Schiøler, Michael Alifrangis, Uriel Kitron, Flemming Konradsen
Neglected Tropical Diseases
Angola is grappling with a yellow fever outbreak, which has infected more than 450 people and killed 178 – the first epidemic of the disease to hit the country in 30 years. The outbreak, which was first reported in the capital city Luanda in December 2015, has since spread to 6 of the country’s 18
Unexplained meat bans can alienate people and hurt livelihoods. Salome Bukachi proposes ways to improve response.
by Peter J. Hotez The United States Gulf Coast’s current risk to Zika transmitted by Aedes aegypti mosquitoes can be traced back to some important federal health policy decisions made during the 1960s.
by Thomas J. Hladish, Carl A.
by Robert C. Reiner Jr., Nicole Achee, Roberto Barrera, Thomas R. Burkot, Dave D
by Rebecca Du, Peter J. Hotez, Waleed S.
by Kateřina Leštinová, Miroslava Soldánová, Tomáš Scholz, Roman Kuchta Background Tapeworms of the order Diphyllobothriidea are parasites of tetrapods and several species may infect man and cause neglected human disease called diphyllobothriosis. Identification of human-infecting diphyllobothriid cestodes is difficult because of their morphological uniformity, which concerns also their eggs in stool samples.
by Michael Käser, Christine Maure, Beatrice M. M.
by Manuel Espinosa, Diego Weinberg, Camilo H. Rotela, Francisco Polop, Marcelo Abril, Carlos Marcelo Scavuzzo Background Since 2009, Fundación Mundo Sano has implemented an Aedes aegypti Surveillance and Control Program in Tartagal city (Salta Province, Argentina). The purpose of this study was to analyze temporal dynamics of Ae.
by Elodie Petitdidier, Julie Pagniez, Gérard Papierok, Philippe Vincendeau, Jean-Loup Lemesre, Rachel Bras-Gonçalves Preventive vaccination is a highly promising strategy for interrupting leishmaniasis transmission that can, additionally, contribute to elimination. A vaccine formulation based on naturally excreted secreted (ES) antigens was prepared from L. infantum promastigote culture supernatant.
by Genevieve Housman, Joanna Malukiewicz, Vanner Boere, Adriana D. Grativol, Luiz Cezar M.
by Victor H. Hu, Philip J.
by Samba O. Sow, Khitam Muhsen, Dilruba Nasrin, William C.
by Jean Gaschignard, Audrey Virginia Grant, Nguyen Van Thuc, Marianna Orlova, Aurélie Cobat, Nguyen Thu Huong, Nguyen Ngoc Ba, Vu Hong Thai, Laurent Abel, Erwin Schurr, Alexandre Alcaïs After sustained exposure to Mycobacterium leprae, only a subset of exposed individuals develops clinical leprosy. Moreover, leprosy patients show a wide spectrum of clinical manifestations that extend from the paucibacillary (PB) to the multibacillary (MB) form of the disease. This “polarization” of leprosy has long been a major focus of investigation for immunologists because of the different immune response in these two forms.
by Fiona R. Strouts, Stephen J.
by Koushik Roy, Sapan Mandloi, Saikat Chakrabarti, Syamal Roy Background Previously we reported that Kala-azar patients show progressive decrease in serum cholesterol as a function of splenic parasite burden. Splenic macrophages (MΦ) of Leishmania donovani (LD) infected mice show decrease in membrane cholesterol, while LD infected macrophages (I-MΦ) show defective T cell stimulating ability that could be corrected by liposomal delivery of cholesterol. T helper cells recognize peptide antigen in the context of class II MHC molecule.