Neglected Tropical Diseases

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Exclusive Q&A: Quarantine Ethics

Global Health NOW | After news broke of Liberia’s aggressive quarantine of a slum in Monrovia, Global Health NOW associate editor Dayna Kerecman Myers had a few Read More

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#NEJM on the #Ebola Outbreak

The New England Journal of Medicine has issued several perspective pieces and brief reports about the Ebola Outbreak.  Resources include an interactive map detailing Ebola cases Read More

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Humanosphere: Ebola outbreak’s negative impact on maternal mortality

The Awful Ebola-Maternal Mortality Nexus…You don’t need ebola to die from it. Reporting from Monrovia, Jina Moore describes how fear of ebola and a broken health system are killing pregnant women. “Liberia has one of the highest rates of maternal death in the world. Giving birth here is always risky, even when you can count

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Exclusive Q&A: Quarantine Ethics

africa-map-wiki-Author-Hristov

Global Health NOW | After news broke of Liberia’s aggressive quarantine of a slum in Monrovia, Global Health NOW associate editor Dayna Kerecman Myers had a few Read More


The Effect of (-)-Epigallocatechin 3-O – Gallate In Vitro and In Vivo in Leishmania…

by Job D. F. Inacio, Luiza Gervazoni, Marilene M


Characterization of Digestive Involvement in Patients with Chronic T. cruzi Infection in…

by María-Jesús Pinazo, Gloria Lacima, José-Ignacio Elizalde, Elizabeth-Jesús Posada, Fausto Gimeno, Edelweiss Aldasoro, María-Eugenia Valls, Joaquim Gascon Background Digestive damage due to Chagas disease (CD) occurs in 15–20% of patients diagnosed as a result of peristaltic dysfunction in some endemic areas. The symptoms of chronic digestive CD are non-specific, and there are numerous confounders. Diagnosis of CD may easily be missed if symptoms are not evaluated by a well trained physician.


Isolation and Characterization of Two Novel Plasmids from Pathogenic Leptospira interrogans…

by Wei-Nan Zhu, Li-Li Huang, Ling-Bing Zeng, Xu-Ran Zhuang, Chun-Yan Chen, Yan-Zhuo Wang, Jin-Hong Qin, Yong-Zhang Zhu, Xiao-Kui Guo Background Previous genomic analysis of pathogenic Leptospira has identified two circular chromosomes but no plasmid. This study aims to investigate potential extrachromosomal elements of L.interrogans serovar Canicola strain Gui44. Methodology Two novel plasmids, pGui1 and pGui2, were isolated from the pathogenic strain Gui44, using a modified alkaline lysis method.


A Panel of Trypanosoma brucei Strains Tagged with Blue and Red-Shifted Luciferases for…

by Nick Van Reet, Hélène Van de Vyver, Patient Pati Pyana, Anne Marie Van der Linden, Philippe Büscher Background Genetic engineering with luciferase reporter genes allows monitoring Trypanosoma brucei (T.b.) infections in mice by in vivo bioluminescence imaging (BLI). Until recently, luminescent T.b.


HIV-Associated Histoplasmosis Early Mortality and Incidence Trends: From Neglect to Priority

by Antoine Adenis, Mathieu Nacher, Matthieu Hanf, Vincent Vantilcke, Rachida Boukhari, Denis Blachet, Magalie Demar, Christine Aznar, Bernard Carme, Pierre Couppie Background Histoplasmosis is an endemic fungal infection in French Guiana. It is the most common AIDS-defining illness and the leading cause of AIDS-related deaths. Diagnosis is difficult, but in the past 2 decades, it has improved in this French overseas territory which offers an interesting model of Amazonian pathogen ecology.


The 2012 Madeira Dengue Outbreak: Epidemiological Determinants and Future Epidemic Potential

by José Lourenço, Mario Recker Dengue, a vector-borne viral disease of increasing global importance, is classically associated with tropical and sub-tropical regions around the world. Urbanisation, globalisation and climate trends, however, are facilitating the geographic spread of its mosquito vectors, thereby increasing the risk of the virus establishing itself in previously unaffected areas and causing large-scale epidemics. On 3 October 2012, two autochthonous dengue infections were reported within the Autonomous Region of Madeira, Portugal


G20 Countries Account For ‘Lion’s Share’ Of NTDs, Expert Says

The Guardian: Wealthier countries home to ‘lion’s share’ of neglected tropical diseases “The international community needs to stop looking at neglected tropical diseases (NTDs) as a sub-Saharan African problem and realize that the G20 countries are now home to the ‘lion’s share’ of the dangerous, debilitating, yet low-profile illnesses, a U.S. expert has warned…” (Jones,…More


#NEJM on the #Ebola Outbreak

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The New England Journal of Medicine has issued several perspective pieces and brief reports about the Ebola Outbreak.  Resources include an interactive map detailing Ebola cases Read More


Worms Contribute To Malnutrition, PLOS Article Shows

Global Network for Neglected Tropical Diseases’ “End The Neglect”: The Role of Worms in Malnutrition Deborah Elson, communications officer for the Global Network and the Sabin Vaccine Institute, discusses an article published in PLOS NTDs that shows how worms are linked to neglected tropical disease burden and malnutrition (8/18).


Humanosphere: Ebola outbreak’s negative impact on maternal mortality

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The Awful Ebola-Maternal Mortality Nexus…You don’t need ebola to die from it. Reporting from Monrovia, Jina Moore describes how fear of ebola and a broken health system are killing pregnant women. “Liberia has one of the highest rates of maternal death in the world. Giving birth here is always risky, even when you can count


Do we really need a new drug or vaccine for Ebola?

I get particularly excited when I see Global Health issues being debated in mainstream magazines and newspapers, and since the outbreak of Ebola has captured global attention, there has been no shortage of such discussions. Perhaps that is why I am blogging again. Why, the mainstream media asks, can we not curb the spread of this deadly epidemic that is ravaging a few countries in West Africa? Sadly, however, I think there has been too much of reacting to Ebola as though Ebola was just any other global health problem: Ebola is about Poverty, Ebola is about Globalization, or Ebola is about Culture.


WHO Statement on Ebola, travel and transport

WHO

The current Ebola virus disease (EVD) outbreak is believed to have begun in Guinea in December 2013. This outbreak now involves community transmission in Guinea, Liberia and Sierra Leone and recently an ill traveller from Liberia infected a small number of people in Nigeria with whom he had direct contact. On 8 August 2014, WHO declared the Ebola virus disease outbreak in West Africa a Public Health Emergency of International Concern (PHEIC) in accordance with the International Health Regulations (2005).


The Role of Worms in Malnutrition

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; In impoverished communities worldwide, children and pregnant women are especially vulnerable to malnutrition, anemia, impaired cognitive and physical development, and pregnancy complications. As a result, they remain trapped in poverty, facing the socioeconomic consequences of decreased productivity and an inability to work or go to school because of their poor health. But the reason […]


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