Neglected Tropical Diseases



Unprecedented number of medical staff infected with Ebola

The outbreak of Ebola virus disease in west Africa is unprecedented in many ways, including the high proportion of doctors, nurses, and other health care workers who have been infected. To date, more than 240 health care workers have developed the disease in Guinea, Liberia, Nigeria, and Sierra Leone, and more than 120 have died.


Ebola has caused Liberia’s cauldron of dissatisfaction to boil over

Robtel Neajai Pailey | Guardian Development | “Relations between the Liberian state and its citizens were already in crisis before the Ebola outbreak made things Read More


Exclusive Q&A: Quarantine Ethics

Global Health NOW | After news broke of Liberia’s aggressive quarantine of a slum in Monrovia, Global Health NOW associate editor Dayna Kerecman Myers had a few Read More


Epidemiology of Disappearing Plasmodium vivax Malaria: A Case Study in Rural Amazonia

by Susana Barbosa, Amanda B. Gozze, Nathália F. Lima, Camilla L.

Visceral Leishmaniasis and HIV Coinfection: Time for Concerted Action

by Johan van Griensven, Ed E. Zijlstra, Asrat Hailu

Sporotrichosis: An Emerging Neglected Opportunistic Infection in HIV-Infected Patients in Rio…

by Dayvison Francis Saraiva Freitas, Antonio Carlos Francesconi do Valle, Margarete Bernardo Tavares da Silva, Dayse Pereira Campos, Marcelo Rosandiski Lyra, Rogerio Valls de Souza, Valdiléa Gonçalves Veloso, Rosely Maria Zancopé-Oliveira, Francisco Inácio Bastos, Maria Clara Gutierrez Galhardo Sporotrichosis associated with zoonotic transmission remains a relevant public health problem in Rio de Janeiro, Brazil, affecting a large at-risk population, which includes HIV-infected individuals. We assessed patients co-infected by Sporothrix spp. and HIV over time in the context of an unabated sporotrichosis epidemic.

Dengue Therapeutics, Chemoprophylaxis, and Allied Tools: State of the Art and Future Directions

by James Whitehorn, Sophie Yacoub, Katherine L. Anders, Louis R. Macareo, M.

Paracoccidioides lutzii Plp43 Is an Active Glucanase with Partial Antigenic Identity with P….

by Natanael P. Leitão, Milene C.

Toxocariasis in North America: A Systematic Review

by Rachel M. Lee, Laura B. Moore, Maria Elena Bottazzi, Peter J.

Prevalence and Risk Factors for Echinococcal Infection in a Rural Area of Northern Chile: A…

by Gerardo Acosta-Jamett, Thomas Weitzel, Belgees Boufana, Claudia Adones, Andrea Bahamonde, Katia Abarca, Philip S. Craig, Ingrid Reiter-Owona Background Hydatidosis is a zoonotic disease of worldwide distribution caused by Echinococcus granulosus.

The Prawn Macrobrachium vollenhovenii in the Senegal River Basin: Towards Sustainable…

by Amit Savaya Alkalay, Ohad Rosen, Susanne H. Sokolow, Yacinthe P. W.

Optimized Multilocus Sequence Typing (MLST) Scheme for Trypanosoma cruzi

by Patricio Diosque, Nicolás Tomasini, Juan José Lauthier, Louisa Alexandra Messenger, María Mercedes Monje Rumi, Paula Gabriela Ragone, Anahí Maitén Alberti-D’Amato, Cecilia Pérez Brandán, Christian Barnabé, Michel Tibayrenc, Michael David Lewis, Martin Stephen Llewellyn, Michael Alexander Miles, Matthew Yeo Trypanosoma cruzi, the aetiological agent of Chagas disease possess extensive genetic diversity. This has led to the development of a plethora of molecular typing methods for the identification of both the known major genetic lineages and for more fine scale characterization of different multilocus genotypes within these major lineages. Whole genome sequencing applied to large sample sizes is not currently viable and multilocus enzyme electrophoresis, the previous gold standard for T.

Correction: Risk Factors and Spatial Distribution of Schistosoma mansoni Infection among…

by The PLOS Neglected Tropical Diseases Staff

Viral Aetiology of Central Nervous System Infections in Adults Admitted to a Tertiary Referral…

by Le Van Tan, Le Hong Thai, Nguyen Hoan Phu, Ho Dang Trung Nghia, Ly Van Chuong, Dinh Xuan Sinh, Nguyen Duy Phong, Nguyen Thi Hoang Mai, Dinh Nguyen Huy Man, Vo Minh Hien, Nguyen Thanh Vinh, Jeremy Day, Nguyen Van Vinh Chau, Tran Tinh Hien, Jeremy Farrar, Menno D. de Jong, Guy Thwaites, H. Rogier van Doorn, Tran Thi Hong Chau Background Central nervous system (CNS) infections are important diseases in both children and adults worldwide

Non-Participation during Azithromycin Mass Treatment for Trachoma in The Gambia: Heterogeneity…

by Tansy Edwards, Elizabeth Allen, Emma M. Harding-Esch, John Hart, Sarah E.

Case Report of Two Cases of Fever, Rash, and Organ Involvement during the Treatment of Leprosy

by Hong Liu, Chuan Wang, Tongsheng Chu, Parimi Leela Rani, Debao Yu, Xi’an Fu, Mingfei Chen, Shumin Chen, Furen Zhang

A Single Crossing-Over Event in Voltage-Sensitive Na+ Channel Genes May Cause Critical Failure…

by Koichi Hirata, Osamu Komagata, Kentaro Itokawa, Atsushi Yamamoto, Takashi Tomita, Shinji Kasai The voltage-sensitive sodium (Na+) channel (Vssc) is the target site of pyrethroid insecticides. Pest insects develop resistance to this class of insecticide by acquisition of one or multiple amino acid substitution(s) in this channel. In Southeast Asia, two major Vssc types confer pyrethroid resistance in the dengue mosquito vector Aedes aegypti, namely, S989P+V1016G and F1534C

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