Neglected Tropical Diseases

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Insecticidal Paints: A Realistic Approach to Vector Control?

by Karin L. Schiøler, Michael Alifrangis, Uriel Kitron, Flemming Konradsen

News in the Humanosphere: Angola suffers worst Yellow Fever outbreak in 30 years

Angola is grappling with a yellow fever outbreak, which has infected more than 450 people and killed 178 – the first epidemic of the disease to hit the country in 30 years. The outbreak, which was first reported in the capital city Luanda in December 2015, has since spread to 6 of the country’s 18

View on Poverty: Rift Valley fever fight is flawed

Unexplained meat bans can alienate people and hurt livelihoods. Salome Bukachi proposes ways to improve response.

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The relationship between entomological indicators of <i>Aedes aegypti</i> abundance…

by Elizabeth A. Cromwell, Steven T. Stoddard, Christopher M


Dengue seroprevalence, seroconversion and risk factors in Dhaka, Bangladesh

by Parnali Dhar-Chowdhury, Kishor Kumar Paul, C. Emdad Haque, Shakhawat Hossain, L.


Interdisciplinary approach at the primary healthcare level for Bolivian immigrants with Chagas…

by Maria Aparecida Shikanai Yasuda, Camila Gonçalves Sátolo, Noemia Barbosa Carvalho, Magda Maya Atala, Rosario Quiroga Ferrufino, Ruth Moreira Leite, Célia Regina Furucho, Expedito Luna, Rubens Antonio Silva, Marcia Hage, Caroline Medeji Ramos de Oliveira, Felipe Delatorre Busser, Vera Lucia Teixeira de Freitas, Dalva Marli Valerio Wanderley, Luzia Martinelli, Sonia Regina Almeida, Pedro Albajar Viñas, Nivaldo Carneiro Jr. Background/Methods In a pioneering cross-sectional study among Bolivian immigrants in the city of São Paulo, Brazil, the epidemiological profile, clinical manifestations and morbidity of Chagas disease were described. The feasibility of the management of Chagas disease at primary healthcare clinics using a biomedical and psychosocial interdisciplinary approach was also tested.


Immune response of rats vaccinated orally with various plant-expressed recombinant cysteine…

by Malgorzata Kesik-Brodacka, Agnieszka Lipiec, Monika Kozak Ljunggren, Luiza Jedlina, Katarzyna Miedzinska, Magdalena Mikolajczak, Andrzej Plucienniczak, Andrzej B. Legocki, Halina Wedrychowicz Background Cysteine proteinases of Fasciola hepatica are important candidates for vaccine antigens because of their role in fluke biology and host-parasite relationships.


Performance of TcI/TcVI/TcII Chagas-Flow ATE-IgG2a for universal and genotype-specific…

by Glaucia Diniz Alessio, Fernanda Fortes de Araújo, Denise Fonseca Côrtes, Policarpo Ademar Sales Júnior, Daniela Cristina Lima, Matheus de Souza Gomes, Laurence Rodrigues do Amaral, Marcelo Antônio Pascoal Xavier, Andréa Teixeira-Carvalho, Olindo Assis Martins-Filho, Marta de Lana Distinct Trypanosoma cruzi genotypes have been considered relevant for patient management and therapeutic response Chagas disease. However, typing strategies for genotype-specific serodiagnosis of Chagas disease are still unavailable and requires standardization for practical application. In this study, an innovative TcI/TcVI/TcII Chagas Flow ATE-IgG2a technique was developed with applicability for universal and genotype-specific diagnosis of T


The rise and fall of rabies in Japan: A quantitative history of rabies epidemics in Osaka…

by Aiko Kurosawa, Kageaki Tojinbara, Hazumu Kadowaki, Katie Hampson, Akio Yamada, Kohei Makita Japan has been free from rabies since the 1950s. However, during the early 1900s several large-scale epidemics spread throughout the country.


Correction: Metformin exhibits preventive and therapeutic efficacy against experimental cystic…

by Julia A. Loos, Valeria A. Dávila, Christian Rodriguez Rodrigues, Romina Petrigh, Jorge A.


Using simulation to aid trial design: Ring-vaccination trials

by Matt David Thomas Hitchings, Rebecca Freeman Grais, Marc Lipsitch Background The 2014–6 West African Ebola epidemic highlights the need for rigorous, rapid clinical trial methods for vaccines. A challenge for trial design is making sample size calculations based on incidence within the trial, total vaccine effect, and intracluster correlation, when these parameters are uncertain in the presence of indirect effects of vaccination.


<i>PLOS Neglected Tropical Diseases</i> 2016 Reviewer and Editorial Board Thank You

See the original post:  <i>PLOS Neglected Tropical Diseases</i> 2016 Reviewer and Editorial Board Thank You


H<sup>+</sup> channels in embryonic <i>Biomphalaria glabrata</i> cell…

by Brandon J. Wright, Utibe Bickham-Wright, Timothy P. Yoshino, Meyer B.


Evaluation of radiation sensitivity and mating performance of <i>Glossina…

by Chantel J. de Beer, Percy Moyaba, Solomon N.


Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid…

by Chantal Reigada, Edward A. Valera-Vera, Melisa Sayé, Andrea E.


Barriers to dog rabies vaccination during an urban rabies outbreak: Qualitative findings from…

by Ricardo Castillo-Neyra, Joanna Brown, Katty Borrini, Claudia Arevalo, Michael Z. Levy, Alison Buttenheim, Gabrielle C. Hunter, Victor Becerra, Jere Behrman, Valerie A


Experimental <i>Bothrops atrox</i> envenomation: Efficacy of antivenom therapy and…

by Gabriella Neves Leal Santos Barreto, Sâmella Silva de Oliveira, Isabelle Valle dos Anjos, Hipocrates de Menezes Chalkidis, Rosa Helena Veras Mourão, Ana Maria Moura da Silva, Ida Sigueko Sano-Martins, Luis Roberto de Camargo Gonçalves Bothrops atrox snakes are the leading cause of snake bites in Northern Brazil. The venom of this snake is not included in the antigen pool used to obtain the Bothrops antivenom. There are discrepancies in reports on the effectiveness of this antivenom to treat victims bitten by B


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