Neglected Tropical Diseases


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Validation of a Microsphere Immunoassay for Serological Leptospirosis Diagnosis

by Sarah J. Wynwood, Mary-Anne A. Burns, Glenn C

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Chikungunya Virus & the Global Spread of Mosquito-Borne Disease (NEJM Review & Graphic)

This week, The New England Journal of Medicine features an excellent review article and interactive graphic on the recent emergence and spread of Chikungunya Virus. Read More

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January WHO Bulletin

This month’s bulletin features articles about the following: • The Ebola epidemic:   – a turning point for global health   – relects the global health workforce crisis   – vaccine Read More


The Distribution of Ocular Chlamydia Prevalence across Tanzanian Communities Where Trachoma Is…

by Salman A. Rahman, Sheila K.

Anthelmintic Activity In Vivo of Epiisopiloturine against Juvenile and Adult Worms of…

by Maria A. Guimarães, Rosimeire N. de Oliveira, Leiz M.

Genetic Recombination between Human and Animal Parasites Creates Novel Strains of Human…

by Wendy Gibson, Lori Peacock, Vanessa Ferris, Katrin Fischer, Jennifer Livingstone, James Thomas, Mick Bailey Genetic recombination between pathogens derived from humans and livestock has the potential to create novel pathogen strains, highlighted by the influenza pandemic H1N1/09, which was derived from a re-assortment of swine, avian and human influenza A viruses. Here we investigated whether genetic recombination between subspecies of the protozoan parasite, Trypanosoma brucei, from humans and animals can generate new strains of human pathogen, T. b

Mycetoma in the Sudan: An Update from the Mycetoma Research Centre, University of Khartoum,…

by Ahmed Fahal, EL Sheikh Mahgoub, Ahmed M. EL Hassan, Manar Elsheikh Abdel-Rahman This communication reports on the Mycetoma Research Centre of the University of Khartoum, Sudan experience on 6,792 patients seen during the period 1991–2014.The patients were predominately young (64% under 30 years old) males (76%). The majority (68%) were from the Sudan mycetoma belt and 28% were students.

Cessation of Mass Drug Administration for Lymphatic Filariasis in Zanzibar in 2006: Was…

by Maria P. Rebollo, Khalfan A.

Co-endemicity of Loiasis and Onchocerciasis in Rain Forest Communities in Southwestern Nigeria

by Olusola Ojurongbe, Akeem Abiodun Akindele, Monsuru Adebayo Adeleke, Matthew Oyebode Oyedeji, Samuel Adeyinka Adedokun, Josephine Folashade Ojo, Callistus Adewale Akinleye, Oloyede Samuel Bolaji, Olusegun Adelowo Adefioye, Oluwaseyi Adegboyega Adeyeba Background Loiasis is currently receiving attention as a disease of public health importance because of the possibility of increased risk of developing neurologic serious adverse event following mass ivermectin treatment against onchocerciasis in individual co-infected with Onchocerca volvulus and Loa loa. Methodology/Principal Findings Rapid assessment procedure for loiasis (RAPLOA) was conducted in 12 communities covering the 3 senatorial districts of Osun State, Nigeria.

Costs Of Using “Tiny Targets” to Control Glossina fuscipes fuscipes, a Vector of Gambiense…

by Alexandra P. M. Shaw, Inaki Tirados, Clement T.

Complex Epidemiology of a Zoonotic Disease in a Culturally Diverse Region: Phylogeography of…

by Daniel L. Horton, Lorraine M. McElhinney, Conrad M.

Interaction of ATP with a Small Heat Shock Protein from Mycobacterium leprae: Effect on Its…

by Sandip Kumar Nandi, Ayon Chakraborty, Alok Kumar Panda, Sougata Sinha Ray, Rajiv Kumar Kar, Anirban Bhunia, Ashis Biswas Adenosine-5’-triphosphate (ATP) is an important phosphate metabolite abundantly found in Mycobacterium leprae bacilli. This pathogen does not derive ATP from its host but has its own mechanism for the generation of ATP. Interestingly, this molecule as well as several antigenic proteins act as bio-markers for the detection of leprosy.

Is Chronic Suppurative Otitis Media a Neglected Tropical Disease?

by Michael G. Li, Peter J.

Geographic Distribution and Mortality Risk Factors during the Cholera Outbreak in a Rural…

by Anne-Laure Page, Iza Ciglenecki, Ernest Robert Jasmin, Laurence Desvignes, Francesco Grandesso, Jonathan Polonsky, Sarala Nicholas, Kathryn P. Alberti, Klaudia Porten, Francisco J. Luquero Background In 2010 and 2011, Haiti was heavily affected by a large cholera outbreak that spread throughout the country.

Intravenous Therapy Duration and Outcomes in Melioidosis: A New Treatment Paradigm

by Matthew C. Pitman, Tara Luck, Catherine S. Marshall, Nicholas M

Correction: Leishmania-HIV Co-infection: Clinical Presentation and Outcomes in an Urban Area in…

by The PLOS Neglected Tropical Diseases Staff

Predominant Leptospiral Serogroups Circulating among Humans, Livestock and Wildlife in…

by Justine A. Assenga, Lucas E.

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