Neglected Tropical Diseases

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What Makes Community Engagement Effective?: Lessons from the Eliminate Dengue Program

by Pamela A. Kolopack, Janet A.

leptospirosis wiki

Validation of a Microsphere Immunoassay for Serological Leptospirosis Diagnosis

by Sarah J. Wynwood, Mary-Anne A. Burns, Glenn C

Chikungunya map wiki

Chikungunya Virus & the Global Spread of Mosquito-Borne Disease (NEJM Review & Graphic)

This week, The New England Journal of Medicine features an excellent review article and interactive graphic on the recent emergence and spread of Chikungunya Virus. Read More

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Echinococcosis: An Economic Evaluation of a Veterinary Public Health Intervention in Rural…

by Janna M. Schurer, Ellen Rafferty, Marwa Farag, Wu Zeng, Emily J.


Suppression of a Field Population of Aedes aegypti in Brazil by Sustained Release of Transgenic…

by Danilo O. Carvalho, Andrew R. McKemey, Luiza Garziera, Renaud Lacroix, Christl A.


Population Pharmacokinetics of an Indian F(ab’)2 Snake Antivenom in Patients with Russell’s…

by Geoffrey K. Isbister, Kalana Maduwage, Ana Saiao, Nicholas A. Buckley, Shaluka F


Development of a Biosensor-Based Rapid Urine Test for Detection of Urogenital Schistosomiasis

by Kathleen E. Mach, Ruchika Mohan, Shailja Patel, Pak Kin Wong, Michael Hsieh, Joseph C. Liao


An Epitope-Substituted DNA Vaccine Improves Safety and Immunogenicity against Dengue Virus Type…

by Chung-Tao Tang, Pi-Chun Li, I-Ju Liu, Mei-Ying Liao, Chiung-Yi Chiu, Day-Yu Chao, Han-Chung Wu Dengue virus (DENV), a global disease, is divided into four serotypes (DENV1-4). Cross-reactive and non-neutralizing antibodies against envelope (E) protein of DENV bind to the Fcγ receptors (FcγR) of cells, and thereby exacerbate viral infection by heterologous serotypes via antibody-dependent enhancement (ADE). Identification and modification of enhancing epitopes may mitigate enhancement of DENV infection


Involvement of Tetraspanin C189 in Cell-to-Cell Spreading of the Dengue Virus in C6/36 Cells

by Chao-Fu Yang, Cheng-Hsun Tu, Yin-Ping Lo, Chih-Chieh Cheng, Wei-June Chen Dengue virus (DENV) is naturally transmitted by mosquitoes to humans, infecting cells of both hosts. Unlike in mammalian cells, DENV usually does not cause extremely deleterious effects on cells of mosquitoes. Despite this, clustered progeny virions were found to form infection foci in a high density cell culture.


Functional Activity Limitation and Quality of Life of Leprosy Cases in an Endemic Area in…

by Victor S. Santos, Laudice S. Oliveira, Fabrícia D


Development of an Immunochromatographic Test for Diagnosis of Visceral Leishmaniasis Based on…

by Chun-hua Gao, Yue-tao Yang, Feng Shi, Jun-yun Wang, Dietmar Steverding, Xia Wang Background Visceral leishmaniasis (VL) is a life-threatening disease caused by protozoan parasites of the Leishmania donovani complex. Early case detection followed by adequate treatment is essential to the control of VL. However, the available diagnostic tests are either invasive and require considerable expertise (parasitological demonstration of the parasite in tissue smears) or unable to distinguish between past and active infection (serological methods)


Plasmodium vivax Diversity and Population Structure across Four Continents

by Cristian Koepfli, Priscila T. Rodrigues, Tiago Antao, Pamela Orjuela-Sánchez, Peter Van den Eede, Dionicia Gamboa, Nguyen van Hong, Jorge Bendezu, Annette Erhart, Céline Barnadas, Arsène Ratsimbasoa, Didier Menard, Carlo Severini, Michela Menegon, Bakri Y.


Failure of PCR to Detect Treponema pallidum ssp. pertenue DNA in Blood in Latent Yaws

by Michael Marks, Samantha Katz, Kai-Hua Chi, Ventis Vahi, Yongcheng Sun, David C. Mabey, Anthony W. Solomon, Cheng Y


Identification of Burkholderia pseudomallei Near-Neighbor Species in the Northern Territory of…

by Jennifer L. Ginther, Mark Mayo, Stephanie D. Warrington, Mirjam Kaestli, Travis Mullins, David M


Group Releases 3rd Progress Report On London Declaration On NTDs

Global Network for Neglected Tropical Diseases’ “End the Neglect”: 3rd Progress Report on The London Declaration on Neglected Tropical Diseases Released Kathryn McGrath, communications manager at the Sabin Vaccine Institute, notes, “Uniting to Combat Neglected Tropical Diseases released its third progress report on the London Declaration on Neglected Tropical Diseases on June 25, 2015.” She…More


Wolbachia Reduces the Transmission Potential of Dengue-Infected Aedes aegypti

by Yixin H. Ye, Alison M. Carrasco, Francesca D.


Characterization of the Burkholderia mallei tonB Mutant and Its Potential as a Backbone Strain…

by Tiffany M. Mott, Sudhamathi Vijayakumar, Elena Sbrana, Janice J. Endsley, Alfredo G


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