Neglected Tropical Diseases

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Guinea Worm, Inching Toward Eradication

By Bill Brieger: “Twenty-eight years ago efforts to eradicate guinea worm began in earnest.  It was the UN Water Decade, and there was optimism that Read More

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The World Health Assembly

Dear Colleagues, This week Remco van de Pas flew back and forth between the Netherlands (European elections), Antwerp (ITM) and Geneva (World Health Assembly), and he mailed me it’s been a gruelling week. Read below some of his first comments on the WHA, or ‘The World Health Theatre’, as he calls it.  More might follow early next week. … And finally it has arrived, The World Health Assembly in Geneva! This is something of an annual ritual for me.

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Myanmar’s moment: reaching millions to improve health

By Neeraj Mistry, managing director of the Global Network for Neglected Tropical Diseases Myanmar’s democratic transition and peace and reconciliation process offer the country a unique opportunity Read More

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A Novel MVA Vectored Chikungunya Virus Vaccine Elicits Protective Immunity in Mice

by James Weger-Lucarelli, Haiyan Chu, Matthew T. Aliota, Charalambos D.


The Global Burden of Disease Study 2010: Interpretation and Implications for the Neglected…

by Peter J. Hotez, Miriam Alvarado, María-Gloria Basáñez, Ian Bolliger, Rupert Bourne, Michel Boussinesq, Simon J.


Unsuspected Leptospirosis Is a Cause of Acute Febrile Illness in Nicaragua

by Megan E. Reller, Elsio A.


Experts Urge Inclusion Of NTDs In Post-2015 Development Agenda

Global Network for Neglected Tropical Diseases’ “End The Neglect”: Global Health Partners Continue to Urge the Inclusion of Neglected Tropical Diseases in the Post-2015 Development Agenda “In a recently released policy brief, partners from the global health community continue to urge all United Nations (U.N.) Member States to ensure that the forthcoming post-2015 framework include…More


Haiti Overcomes Challenges Toward Goal Of Eliminating Lymphatic Filariasis

PLOS Neglected Tropical Diseases: Haiti National Program for the Elimination of Lymphatic Filariasis — A Model of Success in the Face of Adversity Roland Oscar of the Ministry of Public Health and Population in Haiti and colleagues discuss the many challenges faced in achieving success toward eliminating lymphatic filariasis in Haiti (7/17).


Neurocognitive Outcome of Children Exposed to Perinatal Mother-to-Child Chikungunya Virus…

by Patrick Gérardin, Sylvain Sampériz, Duksha Ramful, Brahim Boumahni, Marc Bintner, Jean-Luc Alessandri, Magali Carbonnier, Isabelle Tiran-Rajaoefera, Gilles Beullier, Irénée Boya, Tahir Noormahomed, Jocelyn Okoï, Olivier Rollot, Liliane Cotte, Marie-Christine Jaffar-Bandjee, Alain Michault, François Favier, Monique Kaminski, Alain Fourmaintraux, Xavier Fritel Background Little is known about the neurocognitive outcome in children exposed to perinatal mother-to-child Chikungunya virus (p-CHIKV) infection. Methods The CHIMERE ambispective cohort study compared the neurocognitive function of 33 p-CHIKV-infected children (all but one enrolled retrospectively) at around two years of age with 135 uninfected peers (all enrolled prospectively). Psychomotor development was assessed using the revised Brunet-Lezine scale, examiners blinded to infectious status


Visceral Leishmaniasis as an AIDS Defining Condition: Towards Consistency across WHO Guidelines

by Johan van Griensven, Koert Ritmeijer, Lutgarde Lynen, Ermias Diro


In Vitro and In Vivo Miltefosine Susceptibility of a Leishmania amazonensis Isolate from a…

by Adriano C. Coelho, Cristiana T.


Oroya Fever and Verruga Peruana: Bartonelloses Unique to South America

by Michael F. Minnick, Burt E. Anderson, Amorce Lima, James M.


Leishmania amazonensis Amastigotes Highly Express a Tryparedoxin Peroxidase Isoform That…

by Calvin A. Henard, Eric D.


Detection of Circulating Parasite-Derived MicroRNAs in Filarial Infections

by Lucienne Tritten, Erica Burkman, Andrew Moorhead, Mohammed Satti, James Geary, Charles Mackenzie, Timothy Geary Filarial nematodes cause chronic and profoundly debilitating diseases in both humans and animals. Applications of novel technology are providing unprecedented opportunities to improve diagnosis and our understanding of the molecular basis for host-parasite interactions. As a first step, we investigated the presence of circulating miRNAs released by filarial nematodes into the host bloodstream.


Long-Term and Seasonal Dynamics of Dengue in Iquitos, Peru

by Steven T. Stoddard, Helen J. Wearing, Robert C


Eosinophil Granule Proteins ECP and EPX as Markers for a Potential Early-Stage Inflammatory…

by Charles Emile Ramarokoto, Anna Overgaard Kildemoes, Bodo Sahondra Randrianasolo, Pascaline Ravoniarimbinina, Vololomboahangy Elisabeth Ravaoalimalala, Peter Leutscher, Eyrun Floerecke Kjetland, Birgitte Jyding Vennervald Background Genital granulomas induced by Schistosoma haematobium eggs can manifest as different lesion types visible by colposcopy; rubbery papules (RP), homogenous sandy patches (HSP) and grainy sandy patches (GSP). Pronounced tissue eosinophilia is a candidate marker for active S.


Transcriptome Sequencing and Developmental Regulation of Gene Expression in Anopheles aquasalis

by André L. Costa-da-Silva, Osvaldo Marinotti, José M. C.


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