Realistic portrayal of the scientific community needed to combat science denial

With the recent release of the movie “Vaxxed: From Cover-Up to Catastrophe,” I’m seeing a few blog posts and articles pop up about the hegemonic Read More

Science, global health, and irrational health behaviors

Ed. Note: Sara Gorman will be joining us once a month to highlight different aspects of her forthcoming book on science denialism.  Have you ever Read More

Lifting the Patent Barrier to New Drugs and Energy Sources – The New York Times

Strict patents on technology have had the effect of hindering global progress in some fields, especially in combating disease and climate change. Source: Lifting the Read More


Typhoid fever: a past, present, and future threat

For most communities in high-resource countries, typhoid fever is a distant memory. While it used to rampage major cities in the United States and Europe, typhoid fever was largely stamped out in the 1940s with the advent of antibiotics and improved sanitation. And for international travelers, two typhoid vaccines available at the local clinic eliminate […] ; ; ; ;Related StoriesLes leçons de la ligne de frontPATH is at SXSWHow to survive birth in one of the world’s hardest places ;

Yellow Fever Vaccination Response

Authors: Jennie Harris, Kimberley Fox March 16, 2017 Kim Fox In December 2015, a yellow fever outbreak started in Angola and quickly spread within the country and to its neighbor, the Democratic Republic of Congo (DRC). Laboratory testing confirmed 962 cases, but there were thousands of suspected cases, making this the largest reported outbreak in 30 years. A critical aspect to yellow fever outbreak response is vaccination campaigns in the affected areas. One dose of yellow fever vaccine is capable of providing lifelong protection. Thus the World Health Organization (WHO) keeps a stockpile of 6 million yellow fever vaccine doses for outbreak response

Polio Eradication Efforts Hampered By Conspiracy Theories, Terrorism

Motherboard: Conspiracy Theories Are the Reason We Still Have Polio “…The last countries with polio have some important commonalities: They are rankled by terrorism that threatens health workers and makes it difficult to disseminate vaccines. But the root of this is often based in something else entirely: conspiracy theories that have grown out of stark…More

Inaugural Access To Vaccines Index Ranks Companies Based On Efforts To Expand Immunization…

New York Times: Vaccine Makers Ranked on Pricing and Research “The pharmaceutical companies GlaxoSmithKline and Sanofi sell the most vaccines and earn the most money doing so, while the Serum Institute of India sells the most vaccines at a discount, according to the first Access to Vaccines Index, which was released last week. The new…More

‘Access To Vaccines Index’ Examines Companies’ Investments, Actions To Improve…

Intellectual Property Watch: First Access To Vaccines Index Published “An ‘Access to Vaccines Index’ was released [Monday] in the Netherlands that claims to ‘reveal the first landscape of vaccine company actions to improve immunization coverage.’ The index ‘finds a high level of diversity in how vaccine companies are improving access to vaccines for people living…More

Vaccine Manufacturers Group Improving Immunization Access In Islamic Nations, Could Serve As…

Los Angeles Times: One way the Islamic world is tackling its problem with childhood vaccines Muhammad Naeem Khan, assistant secretary general of the Organization of Islamic Cooperation “…Most vaccines are imported from developed nations, making them unaffordable for those who need them most in developing nations. And vaccine shortages … only compound the problem. ……More

CDC Maintains Vigilance to Eradicate Polio in Northern Nigeria

Chimeremma Denis Nnadi, MD, MPH, PhD Epidemiologist in the Polio Eradication Branch of the Global Immunization Division Vaccines save lives. Today, millions of children have a chance at surviving and living healthy, productive thanks to the introduction and increasingly widespread use of vaccines against major diseases that cripple and kill children over the last few decades. These diseases include polio, diphtheria, pertussis, tetanus, influenza and measles. The essence of our work could be seen in CDC’s commitment to eradicate polio and reduce other vaccine-preventable diseases among children in Nigeria, the most populous country in Africa. More children are surviving and the country is closer than ever to eradicating polio.

‘Global Health Community Must Work Together’ To Achieve Goals Of Global Vaccine Action Plan

The Lancet: Reaching everyone, everywhere with life-saving vaccines Margaret Chan, director general of the WHO; Chris Elias, president of the Global Development Program at the Bill & Melinda Gates Foundation; Anthony Fauci, director of the U.S. National Institute of Allergy and Infectious Diseases; Anthony Lake, executive director of UNICEF; and Seth Berkley, CEO of Gavi,…More

African Business Magazine Examines How Product Development Partnerships Help Drive R&D, Markets…

African Business Magazine: Partnerships to fight disease “…Investing in the discovery, development, and manufacture of drugs to combat tropical and poverty-related diseases in African countries with limited resources to fund research or pay for treatments was a commercial non-starter. … The product development partnership (PDP) model, which emerged in the late 90s, was a response…More

Advances in neglected tropical disease vaccines: Developing relative potency and functional…

by Jill B. Brelsford, Jordan L.

Persistence of immune responses induced by Ebola virus vaccines

The recent devastating outbreak of Ebola virus disease led to the accelerated development of multiple candidate vaccines against this virus, with at least eight entering clinical trials in 2014–16.1 Direct evidence of 100% effectiveness against disease has been demonstrated for VSV-EBOV, a vaccine based on a replicating vesicular stomatitis virus genetically modified to express Ebola virus glycoprotein.2 This vaccine has been granted Breakthrough Therapy Designation status by the US Food and Drug Administration and PRIME status by the European Medicines Agency, and its single-dose regimen and proof of effectiveness from 10 days post-immunisation make it an attractive candidate for use in a responsive campaign (whether it be through ring immunisation around identified cases or as a whole-population intervention).

Typhoid in Africa and vaccine deployment

Typhoid, one of the classic infectious diseases afflicting humanity, is still a relatively common illness in many lower-income and middle-income countries (LMIC).1 The disease is associated with chronic fever that, if not treated, can lead to complications such as intestinal perforation or neurological problems.2 The diagnosis of typhoid is complicated because clinical presentation can be non-specific and can resemble a number of other diseases, such as malaria, typhus, and various viral infections.

Innovators Test Older Approaches For Development Of New Malaria Vaccine

Bill & Melinda Gates Foundation’s “Impatient Optimists”: Innovation: Everything Old is New Again Trevor Mundel, president of global health at the Bill & Melinda Gates Foundation, discusses the work of Miguel Prudencio and his colleagues at Lisbon’s Instituto de Medicina Molecular, who are attempting to use an older approach to vaccine development and apply it…More

The impact of prenatal exposure to parasitic infections and to anthelminthic treatment on…

by Stephen Nash, Alexander J. Mentzer, Swaib A. Lule, Dennison Kizito, Gaby Smits, Fiona R.

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