Vaccines

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Realistic portrayal of the scientific community needed to combat science denial

With the recent release of the movie “Vaxxed: From Cover-Up to Catastrophe,” I’m seeing a few blog posts and articles pop up about the hegemonic Read More

Science, global health, and irrational health behaviors

Ed. Note: Sara Gorman will be joining us once a month to highlight different aspects of her forthcoming book on science denialism.  Have you ever Read More

Lifting the Patent Barrier to New Drugs and Energy Sources – The New York Times

Strict patents on technology have had the effect of hindering global progress in some fields, especially in combating disease and climate change. Source: Lifting the Read More

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African Business Magazine Examines How Product Development Partnerships Help Drive R&D, Markets…

African Business Magazine: Partnerships to fight disease “…Investing in the discovery, development, and manufacture of drugs to combat tropical and poverty-related diseases in African countries with limited resources to fund research or pay for treatments was a commercial non-starter. … The product development partnership (PDP) model, which emerged in the late 90s, was a response…More


Advances in neglected tropical disease vaccines: Developing relative potency and functional…

by Jill B. Brelsford, Jordan L.


Persistence of immune responses induced by Ebola virus vaccines

The recent devastating outbreak of Ebola virus disease led to the accelerated development of multiple candidate vaccines against this virus, with at least eight entering clinical trials in 2014–16.1 Direct evidence of 100% effectiveness against disease has been demonstrated for VSV-EBOV, a vaccine based on a replicating vesicular stomatitis virus genetically modified to express Ebola virus glycoprotein.2 This vaccine has been granted Breakthrough Therapy Designation status by the US Food and Drug Administration and PRIME status by the European Medicines Agency, and its single-dose regimen and proof of effectiveness from 10 days post-immunisation make it an attractive candidate for use in a responsive campaign (whether it be through ring immunisation around identified cases or as a whole-population intervention).


Typhoid in Africa and vaccine deployment

Typhoid, one of the classic infectious diseases afflicting humanity, is still a relatively common illness in many lower-income and middle-income countries (LMIC).1 The disease is associated with chronic fever that, if not treated, can lead to complications such as intestinal perforation or neurological problems.2 The diagnosis of typhoid is complicated because clinical presentation can be non-specific and can resemble a number of other diseases, such as malaria, typhus, and various viral infections.


Innovators Test Older Approaches For Development Of New Malaria Vaccine

Bill & Melinda Gates Foundation’s “Impatient Optimists”: Innovation: Everything Old is New Again Trevor Mundel, president of global health at the Bill & Melinda Gates Foundation, discusses the work of Miguel Prudencio and his colleagues at Lisbon’s Instituto de Medicina Molecular, who are attempting to use an older approach to vaccine development and apply it…More


The impact of prenatal exposure to parasitic infections and to anthelminthic treatment on…

by Stephen Nash, Alexander J. Mentzer, Swaib A. Lule, Dennison Kizito, Gaby Smits, Fiona R.


Gates Foundation Pneumonia Director Discusses India’s Child Immunization Program In Economic…

Economic Times: Gates foundation interested in preventing infectious diseases: Keith Klugman, Bill & Melinda Gates Foundation “India is expected to roll out Pfizer’s 13-valent pneumococcal conjugate vaccine (PCV), Prevnar13, as part of its universal immunization program this year. The vaccine, procured from the Global Alliance for Vaccines and Immunization (Gavi) at $3.2-3.3 (Rs218-225) per dose,…More


Gates Foundation’s Trevor Mundel Discusses CEPI In Scientific American Podcast

Scientific American: Rapid-Response Vaccines for Epidemic Outbreaks In this podcast, “Trevor Mundel, president of global health at the Gates Foundation, talks to Scientific American Editor-in-Chief Mariette DiChristina about the Coalition for Epidemic Preparedness Innovations (CEPI) and the efforts to create vaccine platforms for rapid responses to epidemics…” (DiChristina/Mirsky, 1/30).


Investing In CEPI Could Speed Up Vaccine Development

Nature: Vaccine initiative marks bold resolution Editorial Board “…For too long, the world has fatalistically acquiesced to a status quo in which, because there is no market for vaccines against pathogens that might never cause a major problem, there is no substantial investment in developing vaccines against them. Clearly, private companies cannot be expected to…More


The “Why Vaccines Don’t Cause Autism” Papers

PLOS NTDs co-Editor-in-Chief Peter Hotez lists the key scientific papers refuting the myth that vaccines cause autism I have a unique perspective on the recent headlines surrounding vaccines and their alleged links to autism. I


World Not Yet Prepared To Address Future Ebola Outbreaks, Report Says

STAT: We’re not prepared for future Ebola outbreaks, experts warn “Despite recent headlines declaring the success of an experimental Ebola vaccine, the world is not fully prepared for future epidemics — and not in position to use vaccines to prevent another deadly outbreak, a report published Tuesday warned. The report raised serious concerns about the…More


South-East Asian Nations Using Fractional Polio Vaccine Doses To Conserve Supplies, Ensure…

U.N. News Centre: U.N. agency hails new polio vaccination regimen in South-East Asia that curbs impact on global supply “Amid a global shortage of injectable inactivated polio vaccines (IPV), a new inoculation regimen, employed by governments in the South-East Asian region, involving two fractional vaccine doses — each about a fifth of a full dose…More


Coalition For Epidemic Preparedness Innovations Aims To Develop Disease Prevention, Vaccine…

CNBC: Prepping vaccines is only one way to prepare for the next epidemic “…[T]hough responses [to disease outbreaks] have accelerated, public health defenses don’t galvanize until after the threat has emerged. To get ahead of the next epidemic, a new group has been formed, called CEPI, which stands for Coalition for Epidemic Preparedness Innovations. Its…More


Opinion Piece, Editorial Discuss Availability, Development Of Zika, Ebola Vaccines

New York Times: A Zika Vaccine, but for Whom? Patrick Adams, freelance journalist, and Cameron Nutt, student at Harvard Medical School “The race for a Zika vaccine, one of the most pressing priorities in global health, is at full throttle. More than a dozen companies and government institutions are working to unlock the secrets of…More


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