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“Doing Today’s Work Superbly Well — Treating Ebola with Current Tools”

A perspective piece in the NEJM by several Ebola healthcare providers that discusses common misconceptions such as a lack of material resources or development of novel therapies Read More

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New data, editorials and podcasts on Malaria @NEJM

The July 31st issue of the New England Journal has several new pieces on Malaria – ranging from original articles on “Artemisinin Resistance in P. falciparum” Read More

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How to reach every newborn: three key messages

The Every Newborn Action Plan (ENAP) launched on June 30–July 1, 2014, envisages a world without preventable deaths of newborn infants. The challenge is not technical (effective interventions exist), but instead social. The odds of a child surviving the first month of life are grossly unequal, even within one country, and are affected by wealth, education, caste, and access to health care. Large gains are achievable when interventions reach people who are in need, but this rarely occurs. Without dedicated efforts to reach poor people, ENAP initiatives are likely to favour wealthier people who have the lowest mortality risk.

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[Articles] Assessment of the patient, health system, and population effects of Xpert MTB/RIF…

For Tanzania, this integrated modelling approach predicts that full rollout of Xpert is a cost-effective option for tuberculosis diagnosis and has the potential to substantially reduce the national tuberculosis burden. It also estimates the substantial level of funding that will need to be mobilised to translate this into clinical practice. This approach could be adapted and replicated in other developing countries to inform rational health policy formulation.


[Articles] Burden of typhoid fever in low-income and middle-income countries: a systematic,…

The risk-adjusted typhoid fever burden estimate was more conservative than previous estimates. However, by distinguishing the risk differences, it will allow assessment of the effect at the population level and will facilitate cost-effectiveness calculations for risk-based vaccination strategies for future typhoid conjugate vaccine.


Spatial clustering and risk factors of malaria infections in Ratanakiri Province, Cambodia

Background: Malaria incidence worldwide has steadily declined over the past decades.


Humanized HLA-DR4.RagKO.IL2RgammacKO.NOD (DRAG) mice sustain the complex vertebrate life cycle…

Background: Malaria is a deadly infectious disease affecting millions of people in tropical and sub-tropical countries.


Geographically weighted regression of land cover determinants of Plasmodium falciparum…

Background: Malaria is a mosquito-borne parasitic disease that causes severe mortality and morbidity, particularly in Sub-Saharan Africa.


Ring-shaped calcific constrictive pericarditis strangling the heart: a case report

Constrictive pericarditis is caused by fibrosis and calcification of the pericardium, processes that inhibit diastolic filling of the heart.


Factors affecting acceptability of an email-based intervention to increase fruit and vegetable…

Background: Fresh Facts is a 30-day email-delivered intervention designed to increase the fruit and vegetable consumption of Australian young adults.


Global Health Security and the NTDs

Peter Hotez, co-Editor in Chief of PLOS NTDs, comments on President Obama’s call for global action to prepare for future disease outbreaks and to treat biological threats as issues of national and global security. In a landmark White House summit …The post Global Health Security and the NTDs appeared first on Speaking of Medicine.


[Comment] Planning adaptive health systems: the climate challenge

In 2011, a group of delegates at the UN framework Convention on Climate Change’s 17th Conference of the Parties signed the Durban Declaration, stating “The World Health Organization predicts that unmitigated climate change will lead to significant increases in illness and death brought on by environmental changes.”The Lancet called climate change the greatest global health threat of the 21st Century. The effects of climate change on health have begun to be well established, to make connections between climate and health, planning and policy development continues to occur separately.


[Corrections] Correction to Lancet Glob Health 2014; 2: e508

Naim H, Rana RS. Tharparkar: a forgotten disaster. Lancet Glob Health 2014; 2: e508—In this Correspondence (September 2014), the order of authors was incorrect. The order should have been “Rana RS, Naim H.” This correction has been made as of Sept 25 2014.


[Correspondence] Malnutrition: a neglected but leading cause of child deaths in Papua New…

In resource-limited countries, childhood malnutrition is common and intertwined with poverty. Although substantial financial and political commitments have been made globally in an attempt to reduce childhood mortality, in the Pacific region, including Papua New Guinea, malnutrition remains a neglected but significant cause of childhood deaths.


Factors associated with mortality in HIV-infected people in rural and urban South Africa

Background: Factors associated with mortality in HIV-infected people in sub-Saharan Africa are widely reported.


Sharing perspectives and experiences of doctoral fellows in the first cohort of Consortium for…

Background: Resolution of public health problems in Africa remains a challenge because of insufficient skilled human resource capacity.


‘Scaling-up is a craft not a science’: catalysing scale-up of health innovations in…

Publication date: Available online 28 September 2014 Source:Social Science & Medicine Author(s): Neil Spicer , Dipankar Bhattacharya , Ritgak Dimka , Feleke Fanta , Lindsay Mangham-Jefferies , Joanna Schellenberg , Addis Tamire-Woldemariam , Gill Walt , Deepthi Wickremasinghe Donors and other development partners commonly introduce innovative practices and technologies to improve health in low and middle income countries.


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