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Evidence on feasibility and effective use of mHealth strategies by frontline health workers in…

Objectives Given the large scale adoption and deployment of mobile phones by health services and frontline health workers (FHW), we aimed to review and synthesize the evidence on the feasibility and effectiveness of mobile-based services on healthcare delivery.

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[Comment] Hospitals as debtor prisons

In low-income and middle-income countries (LMICs), systematic research regarding the prevalence and personal consequences of patients who are unable to pay their medical bills has been scarce. However, news headlines frequently tell a simple story of detention—eg, “Kenyan mothers too poor to pay for treatment locked up in hospital”.1 Similar reports are found in Burundi,2 Ghana,3 India,4 Liberia,5 Nigeria,6 the Philippines,7 and Zimbabwe.8

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Can extended cost-effectiveness analysis guide scale-up of essential health services?

Appropriate ways to prioritise investments in health services has always been a challenge for countries, with various devices used based on whether whether the rationale is mainly economic or social. The present health focus calls for both a social and economic perspective, since universal health coverage dimensions are built from both viewpoints. In their Article in The Lancet Global Health, Stéphane Verguet and colleagues present interesting perspectives about the prioritisation of services as countries move towards universal health coverage.

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Minimal Coital Dilution in Accra, Ghana

Background: Coital dilution, the reduction in the coital frequency per partner when an additional ongoing partner is added, may reduce the transmission potential of partnership concurrency for HIV and other sexually transmitted infections.


Partner Characteristics Associated With HIV Acquisition Among Youth in Rakai, Uganda

Background: HIV risk is influenced by multiple factors including the behaviors and characteristics of sexual partners.


Climate change, food systems and population health risks in their eco-social context

The establishment of ecological public health as crucial to modern public health is overdue.


Novel pantothenate derivatives for anti-malarial chemotherapy

Background: A number of synthetic pantothenate derivatives, such as pantothenamides, are known to inhibit the growth of the human malaria parasite Plasmodium falciparum, by interfering with the parasite Coenzyme A (CoA) biosynthetic pathway.


Prevalence of K13-propeller polymorphisms in Plasmodium falciparum from China-Myanmar border in…

Background: The recent emergence and spread of artemisinin resistance in the Greater Mekong Subregion poses a great threat to malaria control and elimination.


Demographic factors associated with smoking cessation during pregnancy in New South Wales,…

Background: Smoking during pregnancy increases the risk of adverse health outcomes for both the mother and the child.


Prevalence of cardiovascular disease risk factors among a Nigerian adult population:…

Background: In Nigeria, reports on the prevalence of modifiable cardiovascular disease (CVD) risk factors are scarce.


Is ‘excess’ mortality in Glasgow an artefact of measurement?

A previous investigation of Glasgow’s excess mortality showed that the (income) deprivation profiles for Glasgow, Liverpool and Manchester were nearly identical.


Implementation and Operational Research: Evaluation of Swaziland’s Hub-and-Spoke Model for…

Background: In 2007, Swaziland initiated a hub-and-spoke model for decentralizing antiretroviral therapy (ART) access.


HIV Infection Is Associated With Increased Risk for Acute Exacerbation of COPD

Background: Poorly controlled HIV infection is associated with increased risk for chronic obstructive pulmonary disease (COPD).


Release of Lungworm Larvae from Snails in the Environment: Potential for Alternative…

by Alessio Giannelli, Vito Colella, Francesca Abramo, Rafael Antonio do Nascimento Ramos, Luigi Falsone, Emanuele Brianti, Antonio Varcasia, Filipe Dantas-Torres, Martin Knaus, Mark T. Fox, Domenico Otranto Background Gastropod-borne parasites may cause debilitating clinical conditions in animals and humans following the consumption of infected intermediate or paratenic hosts. However, the ingestion of fresh vegetables contaminated by snail mucus and/or water has also been proposed as a source of the infection for some zoonotic metastrongyloids (e.g., Angiostrongylus cantonensis)


Bringing Access to the Full Spectrum of Cancer Research: A Call for Papers

by The PLOS Medicine Editors


High Prevalence of HTLV-1 Infection among Japanese Immigrants in Non-endemic Area of Brazil

by Larissa M. Bandeira, Silvia N. O.


Trypanosomiasis-Induced Megacolon Illustrates How Myenteric Neurons Modulate the Risk for Colon…

by Vinicius Kannen, Enio C. de Oliveira, Bruno Zene Motta, Annuar Jose Chaguri, Mariângela Ottoboni Brunaldi, Sérgio B. Garcia Background Trypanosomiasis induces a remarkable myenteric neuronal degeneration leading to megacolon


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