Tag Archives: ebola

Oral Cholera Vaccination in Emergencies: Experiences from Freetown, Republic of Sierra Leone

Dr Denis Marke, CH/EPI Program Manager at the Sierra Leone Ministry of Health shared his experiences from a recent natural disaster at the WHO African Regional Immunization Technical Advisory Group meeting in Johannesburg, 5-8 December 2017. Below find his observations. Heavy rains occurred in the early hours of 14th August 2017 that resulted in flash floods and mudslides that affected three communities (Sugar Loaf, Motomeh, and Kaningo) in the Western Area districts. The mudslides and flash floods blocked water ways and contaminated water sources in several low lying communities of Freetown, the capital city. Both mudslides and flooding destroyed houses, killing many people and displacing thousands of people.

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Development and preliminary evaluation of a multiplexed amplification and next generation…

by Annika Brinkmann, Koray Ergünay, Aleksandar Radonić, Zeliha Kocak Tufan, Cristina Domingo, Andreas Nitsche Background We describe the development and evaluation of a novel method for targeted amplification and Next Generation Sequencing (NGS)-based identification of viral hemorrhagic fever (VHF) agents and assess the feasibility of this approach in diagnostics. Methodology An ultrahigh-multiplex panel was designed with primers to amplify all known variants of VHF-associated viruses and relevant controls. The performance of the panel was evaluated via serially quantified nucleic acids from Yellow fever virus, Rift Valley fever virus, Crimean-Congo hemorrhagic fever (CCHF) virus, Ebola virus, Junin virus and Chikungunya virus in a semiconductor-based sequencing platform.

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SMS-based Ebola Community Surveillance in Sierra Leone

In July 2015, in the aftermath of the Ebola outbreak, local and international Red Cross partners used Magpi to implement a “community event-based surveillance system (CEBS) using SMS”.  The community surveillance began in three districts of the country: Port Loko, Koinadugu and Bonthe. SLRCS volunteers, both community- based volunteers and volunteer supervisors were recruited from their communities and trained in the purpose of CEBS, signs and symptoms of the chosen events and diseases, how to report the cases by SMS to SLRCS headquarter, and trained in the stages of the surveillance from the detection of the cases to the reporting, the verification and the response. The volunteers were expected to be active in their community; inform the community about signs and symptoms and encourage the community members to report to the volunteer if they-or anyone they knew experienced any of these. The volunteers reported the suspected cases including which sign or symptom that was observed and which measures had been taken at community level, and supported the national health authorities in the response.

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The oughtness of care: Fear, stress, and caregiving during the 2000–2001 Ebola outbreak in…

Publication date: December 2017 Source:Social Science & Medicine, Volume 194 Author(s): Sung-Joon Park, Grace Akello In this article we introduce the term oughtness of care to show how caring for sick relatives was experienced in the context of the Ebola outbreak in Gulu, Uganda, in 2000–2001.

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Implementation of a study to examine the persistence of Ebola virus in the body fluids of Ebola…

by Gibrilla Fadlu Deen, Suzanna L. R. McDonald, Jaclyn E

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"We are survivors and not a virus:" Content analysis of media reporting on Ebola…

by Elisabeth Anne-Sophie Mayrhuber, Thomas Niederkrotenthaler, Ruth Kutalek Background The Ebola virus disease epidemic between 2013 and 2016 in West Africa was unprecedented. It resulted in approximately 28.000 cases and 10.000 Ebola survivors.

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Lessons from the West African Ebola epidemic

Conventional wisdom—and an article in the Journal of Medical Ethics reviewed on this blog two years ago—advise that health research should not be conducted during times of crisis. Yes, such conditions compromise the controlled environments that studies typically require to produce reliable results, but they can also threaten the ethical integrity of research. Without institutional mechanisms to hold them accountable, investigators may cut corners, violate standards of privacy and informed consent, and even endanger participants. Disruption in the normal function of medical services can also apply pressure on individuals unable to access care by traditional means to seek it out by participating in risky research.

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Development of a set of community-informed Ebola messages for Sierra Leone

by John Kinsman, Kars de Bruijne, Alpha M. Jalloh, Muriel Harris, Hussainatu Abdullah, Titus Boye-Thompson, Osman Sankoh, Abdul K.

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Rapid qualitative research methods during complex health emergencies: A systematic review of…

Publication date: September 2017 Source:Social Science & Medicine, Volume 189 Author(s): Ginger A.

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Analysis of patient data from laboratories during the Ebola virus disease outbreak in Liberia,…

by Yuki Furuse, Mosoka Fallah, Hitoshi Oshitani, Ling Kituyi, Nuha Mahmoud, Emmanuel Musa, Alex Gasasira, Tolbert Nyenswah, Bernice Dahn, Luke Bawo An outbreak of Ebola virus disease (EVD) in Liberia began in March 2014 and ended in January 2016. Epidemiological information on the EVD cases was collected and managed nationally; however, collection and management of the data were challenging at the time because surveillance and reporting systems malfunctioned during the outbreak.

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Conventional Wisdom versus Actual Outcomes: Challenges in the Conduct of an Ebola Vaccine Trial…


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Liberia’s Fight against Malaria Continues

Liberia was making steady progress against malaria in the years after the civil war. Despite the devastation of Ebola, the health authorities have continued to push against malaria. The DHS Program has released key findings from the 2016 Malaria Information Survey. We have compared those against the 2011 MIS, and while there is progress, much work needs to be done in this highly endemic area – not just in fighting malaria, but in rebuilding health systems damaged by war and Ebola.

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Humanitarian funding: What were 2016’s key trends?

Global spending in response to humanitarian crises reached an estimated US$27.3 billion in 2016. Our Global Humanitarian Assistance Report 2017 provides detailed and comprehensive analysis of what’s behind this. Here are four key trends in where the money comes from and how and where it is delivered – and what this means for current and future funding. A slowdown in global humanitarian funding It’s remarkable that in 2016 international humanitarian funding grew for the fourth consecutive year, but striking how this growth slowed.

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Challenges in preparing and implementing a clinical trial at field level in an Ebola emergency:…

by Sara Carazo Perez, Elin Folkesson, Xavier Anglaret, Abdoul-Habib Beavogui, Emmanuel Berbain, Alseny-Modet Camara, Evelyn Depoortere, Annabelle Lefevre, Piet Maes, Kristian Nødtvedt Malme, Jean-Marie Denis Malvy, Sien Ombelet, Geertrui Poelaert, Daouda Sissoko, Alexis Tounkara, Pierre Trbovic, Pascal Piguet, Annick Antierens Author summary: During the large Ebola outbreak that affected West Africa in 2014 and 2015, studies were launched to evaluate potential treatments for the disease. A clinical trial to evaluate the effectiveness of the antiviral drug favipiravir was conducted in Guinea.

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