Tag Archives: featured content

Diarrhea, the time thief

Diarrhea, the time thief hrandall Mon, 02/12/2018 – 10:56 Feb 12, 2018 Thomas Wierzba Senior Scientist, PATH’s Center for Vaccine Development and Access (CVIA) A child in Sudan receives ORS during a hospital stay for severe diarrhea. PATH/Doune Porter.   Global deaths from diarrhea are falling, rapidly. This is encouraging news—it means that fewer parents are living with the tragedy of a child lost to diarrhea.

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If childhood stunting is a three-legged stool, poor gut health is one leg

If childhood stunting is a three-legged stool, poor gut health is one leg hrandall Wed, 02/07/2018 – 16:42 Feb 07, 2018 defeatDD Dr. Mark Manary, one of the world’s foremost experts in childhood malnutrition, screens children in Chikweo, Malawi. Photo: Carol Lin.   With 155 million stunted children in the world, progress against the complex condition is not coming fast enough to meet the 40 percent reduction target set by the United Nations Sustainable Development Goals. We spoke to Dr.

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icddr,b launches a preemptive strike against cholera with vaccines

icddr,b launches a preemptive strike against cholera with vaccines hrandall Thu, 02/01/2018 – 10:44 Feb 01, 2018 Farasha Bashir Communications Specialist, icddr,b The emergency The Rohingyas are a predominantly Muslim ethnic group who, for centuries, resided in the Buddhist-dominant Rakhine State of Myanmar. However, they are not considered by Myanmar as one of their 135 official ethnic groups and have been denied citizenship since 1982, effectively rendering them stateless.   In August 2017, thousands of Forcibly Displaced Myanmar Nationals (FDMN) fled from Myanmar due to a violent military crackdown. More than 625,000 FDMNs arrived in Cox’s Bazar, the border district of Bangladesh, in what the UN has called the most urgent refugee emergency in the world.     Limited space in registered camps created a vast challenge for Bangladesh where FDMNs have set up ‘home’ in informal shanties made from polythene and bamboo sticks.

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Join PATH in Mexico City for the next VASE Conference!

Join PATH in Mexico City for the next VASE Conference! hrandall Tue, 01/09/2018 – 16:06 Jan 09, 2018 Dr. Richard Walker Director of PATH’s enteric vaccine project Nearly two years ago, I announced PATH’s first international Vaccines Against Shigella and enterotoxigenic Escherichia coli (ETEC) Conference (more commonly known as the VASE Conference), and I blogged about our high hopes and exciting plans for the event. This meeting was the first of its kind, and we really weren’t sure what to expect.

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Going straight to the source for vaccine research

Going straight to the source for vaccine research hrandall Wed, 01/03/2018 – 12:50 Jan 03, 2018 Study team Helsinki University Hospital You might be more used to seeing the shorthand abbreviation for ETEC, one of the leading bacterial causes of diarrhea. The 13-syllable mouthful is a lot to digest: Enterotoxigenic Escherichia coli. I can tell you that it is a mouthful in Finnish, too.   There is currently no vaccine against ETEC, and we’re working to change that. While a vaccine to protect against ETEC would be welcome news to globetrotters who want protection against traveler’s diarrhea, our objective in researching this vaccine is to prevent death and disability in children that ETEC causes, primarily in poor settings.

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DefeatDD’s top ten in 2017

DefeatDD’s top ten in 2017 hrandall Tue, 12/26/2017 – 15:29 Dec 26, 2017 defeatDD Our Toilet Talks campaign was not a blog per se, but it was a major 2017 moment. Check out our new case study summarizing the highlights.   Perhaps you can sense the collective exhale as global health sector news slows for the holiday season. As usual, it’s our favorite time to dig into the analytics and check out your favorite DefeatDD blog posts of the year, always a fun and illuminating activity. This year in particular, it was like looking through a scrapbook of our many 2017 product launches

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The world’s worst cholera outbreak highlights need for long-term solutions

The world’s worst cholera outbreak highlights need for long-term solutions hrandall Fri, 12/01/2017 – 10:08 Dec 01, 2017 Farasha Bashir Communications Specialist, icddr,b In 2015, civil war broke out in Yemen between the government and the rebel movement, triggering a humanitarian crisis that has resulted in more than 70 per cent of the population needing immediate aid and assistance. Yemen is one of the poorest countries in the Arab peninsula, and constant bombings have devastated infrastructure, including roads and hospitals.   One of the most devastating consequences of this war and instability has been the worst cholera outbreak ever recorded. Cholera is an acute diarrhoeal disease that thrives in disadvantaged and unstable environments; it can kill within hours if left untreated. Malnutrition and poor sanitation have made the country vulnerable to cholera, and more than 800,000 civilians have already been affected.

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Killing two bugs with one strategy

Killing two bugs with one strategy hrandall Fri, 11/10/2017 – 11:47 Nov 10, 2017 Laura Kallen Senior Scientific Communications Associate, PATH If pneumonia and diarrhea—the two biggest infectious killers of children worldwide—were personified as serial killers, I imagine that they would look very different. Pneumonia might be tall and spindly, with long, wispy fingers. Diarrhea, on the other hand, would be stocky, thick, and very ugly, a grisly force. Both are horrifying to imagine, but then again, so is the reality. These diseases take 1.5 million young lives every year

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Women lead the way to a healthier India

Women lead the way to a healthier India hrandall Wed, 10/25/2017 – 15:05 Oct 25, 2017 Erika Amaya Digital Communications Officer, PATH On DefeatDD’s trip to India earlier this year, I had the opportunity to meet with many dedicated colleagues working to reduce the toll of childhood diarrhea. As they guided our team through some of the communities most affected by a high burden of infectious disease,  residents shared  their challenges, successes, and hopes for the future.   Through these conversations, I learned that here, women are leading the charge for social change and health.   As our colleague Dr.

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The protective power of vaccines against diarrhea

The protective power of vaccines against diarrhea hrandall Mon, 10/09/2017 – 12:08 Oct 09, 2017 Hope Randall Digital Communications Officer for DefeatDD Nicole Maier, clinical trial coordinator for PATH’s enteric vaccine portfolio, said she got choked up while watching our latest video for the first time. Why? I sat down with her to hear more about her personal take on the video.     Talk to me about why you got emotional watching this video.   You know, it just makes everything about organizing clinical trials, from the stressful to the monotonous, worthwhile in the end.

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Rotavirus vaccine – along with our team – demonstrates efficacy in Indian clinical study

Rotavirus vaccine – along with our team – demonstrates efficacy in Indian clinical study hrandall Tue, 09/26/2017 – 11:13 Sep 26, 2017 Tushar Tewari Senior Medical Officer, CVIA Clinical, and PATH’s Team Leader for the BRV-PV Phase 3 efficacy study As results from a Phase 3 efficacy study in India of the Serum Institute of India Pvt. Ltd. (SIIPL)’s rotavirus vaccine BRV-PV (now known as ROTASIIL) are published in the journal Vaccine, I find myself reflecting on the great partnership that conducted the trial. The Serum Institute and PATH worked with six strong community-based clinical sites, all supported by the Clinical Research Organization, DiagnoSearch. 

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After the floods: Diarrheal disease threats lurk behind natural disasters

After the floods: Diarrheal disease threats lurk behind natural disasters hrandall Fri, 09/22/2017 – 13:49 Sep 22, 2017 defeatDD Hurricanes in the United States and the Caribbean. Floods in South Asia and Yemen. Mudslides in Sierra Leone. The natural disasters of the past month have held many captive: literal captives of flooded houses, cars, roads, and airports. Others have been simply captivated by news of the devastation

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Children: the most persistent and passionate advocates

Children: the most persistent and passionate advocates hrandall Tue, 09/12/2017 – 13:32 Sep 12, 2017 Hope Randall Digital Communications Officer for DefeatDD I have yet to meet a child who did not want to be a grown up.   My four-year-old niece, Lily, loves sharing her expertise with her baby sister, Rosalie, on how to navigate the ways of the world. Fortunately for her mom, Lily is fastidious about cleanliness: “I don’t like germs. We don’t need to give germs to each other.” She thinks it’s fun to help Rosalie wash her hands, loves to help her mommy do the dishes, and is loud and proud about her recent potty training success.   As much as she wants to be a grown up, though, she is still only four years old

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An impossible choice: The dangerous disruption of diarrhea treatment costs

An impossible choice: The dangerous disruption of diarrhea treatment costs hrandall Tue, 09/05/2017 – 10:43 Sep 05, 2017 defeatDD Many families are forced to make the impossible choice between treatment and family finances when their children fall ill with diarrheal disease.   Diarrheal disease isn’t just a medical problem—it’s an economic one, too. We’ve heard from families around the world how the costs of diarrhea treatment can significantly interrupt parents’ livelihoods as well as education, food, and shelter for the rest of the family. A study published in the British Medical Journal provides powerful evidence and deeper insights into the economics of diarrheal disease for families in Malawi. To help break it down, we’re sharing a few of the study’s most fascinating findings

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