Tag Archives: malaria

Effectiveness of two community-based strategies on disease knowledge and health behaviour…

Ghana has developed two community-based strategies that aim to increase access to quality treatment for malaria, diarrhoea and suspected pneumonia, and to improve household and family practices: integrated Com…

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Oral Cholera Vaccination in Emergencies: Experiences from Freetown, Republic of Sierra Leone

Dr Denis Marke, CH/EPI Program Manager at the Sierra Leone Ministry of Health shared his experiences from a recent natural disaster at the WHO African Regional Immunization Technical Advisory Group meeting in Johannesburg, 5-8 December 2017. Below find his observations. Heavy rains occurred in the early hours of 14th August 2017 that resulted in flash floods and mudslides that affected three communities (Sugar Loaf, Motomeh, and Kaningo) in the Western Area districts. The mudslides and flash floods blocked water ways and contaminated water sources in several low lying communities of Freetown, the capital city. Both mudslides and flooding destroyed houses, killing many people and displacing thousands of people.

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Challenges in achieving Maternal and Neonatal Tetanus Elimination: South Sudan Experience

Dr. Anthony Laku who is currently the Immunization Program Officer in the South Sudan Ministry of Health presented the status of efforts to eliminate maternal and neonatal tetanus (MNT) in South Sudan at the fourth meeting of the WHO Regional Immunization Technical Advisory Group held 5-7 December 2017 in Johannesburg, South Africa. A summary of key challenges is shared below. General Challenges to health delivery in South Sudan include a Maternal Mortality Ratio of 2054 per 100,000 live births.

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malERA: An updated research agenda for health systems and policy research in malaria…

by The malERA Refresh Consultative Panel on Health Systems and Policy Research Health systems underpin disease elimination and eradication programmes. In an elimination and eradication context, innovative research approaches are needed across health systems to assess readiness for programme reorientation, mitigate any decreases in effectiveness of interventions (‘effectiveness decay’), and respond to dynamic and changing needs. The malaria eradication research agenda (malERA) Refresh consultative process for the Panel on Health Systems and Policy Research identifies opportunities to build health systems evidence and the tools needed to eliminate malaria from different zones, countries, and regions and to eradicate it globally. The research questions are organised as a portfolio that global health practitioners, researchers, and funders can identify with and support. This supports the promotion of an actionable and more cohesive approach to building the evidence base for scaled-up implementation of findings.

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malERA: An updated research agenda for characterising the reservoir and measuring transmission…

by The malERA Refresh Consultative Panel on Characterising the Reservoir and Measuring Transmission This paper summarises key advances in defining the infectious reservoir for malaria and the measurement of transmission for research and programmatic use since the Malaria Eradication Research Agenda (malERA) publication in 2011. Rapid and effective progress towards elimination requires an improved understanding of the sources of transmission as well as those at risk of infection. Characterising the transmission reservoir in different settings will enable the most appropriate choice, delivery, and evaluation of interventions. Since 2011, progress has been made in a number of areas. The extent of submicroscopic and asymptomatic infections is better understood, as are the biological parameters governing transmission of sexual stage parasites.

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malERA: An updated research agenda for basic science and enabling technologies in malaria…

by The malERA Refresh Consultative Panel on Basic Science and Enabling Technologies Basic science holds enormous power for revealing the biological mechanisms of disease and, in turn, paving the way toward new, effective interventions. Recognizing this power, the 2011 Research Agenda for Malaria Eradication included key priorities in fundamental research that, if attained, could help accelerate progress toward disease elimination and eradication. The Malaria Eradication Research Agenda (malERA) Consultative Panel on Basic Science and Enabling Technologies reviewed the progress, continuing challenges, and major opportunities for future research. The recommendations come from a literature of published and unpublished materials and the deliberations of the malERA Refresh Consultative Panel. These areas span multiple aspects of the Plasmodium life cycle in both the human host and the Anopheles vector and include critical, unanswered questions about parasite transmission, human infection in the liver, asexual-stage biology, and malaria persistence.

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Internet-based biosurveillance methods for vector-borne diseases: Are they novel public health…

by Simon Pollett, Benjamin M. Althouse, Brett Forshey, George W.

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malERA Refresh collection: an updated research agenda for malaria elimination and eradication

PLOS Medicine announces the Malaria Eradication Research Agenda Refresh collection. In 2016, an estimated 216 million cases of malaria and 445 000 deaths occurred in the 91 countries with ongoing malaria transmission, mostly affecting children in

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Towards malaria elimination in Savannakhet, Lao PDR: mathematical modelling driven strategy…

The number of Plasmodium falciparum malaria cases around the world has decreased substantially over the last 15 years, but with the spread of resistance against anti-malarial drugs and insecticides, this decline …

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Seasonal malaria chemoprevention: successes and missed opportunities

Seasonal malaria chemoprevention (SMC) was recommended in 2012 for young children in the Sahel during the peak malaria transmission season.

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Plasmodium falciparum Kelch 13 mutations and treatment response in patients in Hpa-Pun…

Artemisinin resistance, linked to polymorphisms in the Kelch gene on chromosome 13 of Plasmodium falciparum (k13), has outpaced containment efforts in South East Asia.

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The US President’s Malaria Initiative, <i>Plasmodium falciparum</i> transmission…

by Peter Winskill, Hannah C. Slater, Jamie T. Griffin, Azra C. Ghani, Patrick G. T

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Ivermectin susceptibility, sporontocidal effect, and inhibition of time to re-feed in the…

Outdoor malaria transmission hinders malaria elimination efforts in the Amazon region and novel vector control tools are needed.

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Poverty and health among CDC plantation labourers in Cameroon: Perceptions, challenges and…

by Valerie Makoge, Lenneke Vaandrager, Harro Maat, Maria Koelen Creating better access to good quality healthcare for the poor is a major challenge to development. In this study, we examined inter-linkages between poverty and disease, referred to as poverty-related diseases (PRDs), by investigating how Cameroon Development Corporation (CDC) camp dwellers respond to diseases that adversely affect their health and wellbeing. Living in plantation camps is associated with poverty, overcrowding, poor sanitation and the rapid spread of diseases

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