Tag Archives: tuberculosis

Latent tuberculosis infection and associated risk indicators in pastoral communities in…

Research pertaining to the community-based prevalence of latent tuberculosis infection (LTBI) is important to understand the magnitude of this infection.

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Low Prevalence of Tuberculin Skin Test Boosting among Community Residents in Uganda


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Histoplasmosis in Africa: An emerging or a neglected disease?

by Rita O. Oladele, Olusola O. Ayanlowo, Malcolm D.

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What’s coming for health science and policy in 2018? Global experts look ahead in their field

Note: This PLOS Medicine Editorial is appearing in Speaking of Medicine ahead of publication in the journal. The final version will publish on January 30. As the calendar turns to 2018, the PLOS Medicine Editors ask

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Lansoprazole use and tuberculosis incidence in the United Kingdom Clinical Practice Research…

by Tom A. Yates, Laurie A. Tomlinson, Krishnan Bhaskaran, Sinead Langan, Sara Thomas, Liam Smeeth, Ian J. Douglas Background Recent in vitro and animal studies have found the proton pump inhibitor (PPI) lansoprazole to be highly active against Mycobacterium tuberculosis. Omeprazole and pantoprazole have no activity

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Comparison of two cash transfer strategies to prevent catastrophic costs for poor…

by William E. Rudgard, Carlton A. Evans, Sedona Sweeney, Tom Wingfield, Knut Lönnroth, Draurio Barreira, Delia Boccia Background Illness-related costs for patients with tuberculosis (TB) ≥20% of pre-illness annual household income predict adverse treatment outcomes and have been termed “catastrophic.” Social protection initiatives, including cash transfers, are endorsed to help prevent catastrophic costs. With this aim, cash transfers may either be provided to defray TB-related costs of households with a confirmed TB diagnosis (termed a “TB-specific” approach); or to increase income of households with high TB risk to strengthen their economic resilience (termed a “TB-sensitive” approach). The impact of cash transfers provided with each of these approaches might vary.

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<i>Schistosoma</i>, other helminth infections, and associated risk factors in…

by Khadija Said, Jerry Hella, Stefanie Knopp, Tatu Nassoro, Neema Shija, Fatma Aziz, Francis Mhimbira, Christian Schindler, Upendo Mwingira, Anna M. Mandalakas, Karim Manji, Marcel Tanner, Jürg Utzinger, Lukas Fenner Background Despite the high prevalence of helminth infections among preschool-aged children, control programs in sub-Saharan countries primarily focus on school-aged populations. We assessed the prevalence of helminth infections and determined risk factors for infection among preschool-aged children in the urban setting of Dar es Salaam, Tanzania.

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Building and Rebuilding: The National Public Health Laboratory Systems and Services Before and…


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Beware of pharmaceutical companies bearing cheap drugs

Pharmaceutical companies are for-profit enterprises that make their money by selling medicinal drugs. This might seem stupefyingly obvious, but it can get (briefly) obscured when these companies distribute shiny pamphlets suggesting that the promotion of human well-being is their ultimate mission or when they act in seemingly philanthropic ways. Scratch the surface, or just wait until the smoke clears, and the profit motive comes back into view. This is partly why bioethics workers find pharmaceutical companies fascinating and appalling: sometimes they offer a glimpse of what it would be like if powerful multinationals really threw their weight behind public health goals, but only a glimpse, because they inevitably veer off to make money and please their stockholders, sometimes in ways at odds with the ethics of research and health care. They are a kind of ethical rogue element.

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Predictive factors for a one-year improvement in nontuberculous…

by Gilbert Cadelis, Rodolphe Ducrot, Arnaud Bourdin, Nalin Rastogi Background Nontuberculous mycobacterial pulmonary disease (NTM-PD) has become an emerging infectious disease and is responsible for more deaths than tuberculosis in industrialized countries. NTM-PD mortality remains high in some series reportedly ranging from 25% to 40% at five years and often due to unfavorable evolution of NTM-PD despite established treatment. The purpose of our study was to search for early factors that could predict the favorable or unfavorable evolution of NTM-PD at the first year of treatment.

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Patients pathways to tuberculosis diagnosis and treatment in a fragmented health system: a…

India’s Revised National Tuberculosis (TB) Control Programme (RNTCP) offers free TB diagnosis and treatment.

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Public health implications of changing patterns of recruitment into the South African mining…

The triple epidemic of silicosis, tuberculosis and HIV infection among migrant miners from South Africa and neighbouring countries who have worked in the South African mining industry is currently the target o…

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Health for All at the International Institute for Primary Health Care, Ethiopia

The time is ripe for a revitalization of the primary health care (PHC) movement. “Health for All through Primary Health Care” (HFA) was first envisioned at the 1978 International Conference on Primary Health Care (World Health Organization and UNICEF), and was enshrined in the Declaration of Alma-Ata. The HFA goal of bringing essential, affordable, scientifically sound, socially acceptable  health care provided by health workers who are trained to work as a health team and who are responsive to the health needs of the community, guided by strong community engagement by the year 2000 but has not been fully met. Fortunately the vision of Alma-Ata has taken root, sprouted and flourished in a number of locations.

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IAS 2017: X-DR TB emerges in 1990s in South Africa fueled by HIV

Categories: IAS 2017PARIS – Extensively drug resistant tuberculosis emerged and was widely transmitted in South Africa long before it was spotted by public health surveillance efforts, and at least a decade earlier than the first reported outbreak in 2005, a  presentation Monday showed. The start of the spread was , concurrent with the steep rise in both HIV and […](Read more…)

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